CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Coagulation factor X |
Enzyme Information
| 3.4.21.69 |
Protein C (activated).
based on mapping to UniProt P04070
Degradation of blood coagulation factors Va and VIIIa.
-!- One of the gamma-carboxyglutamic acid-containing coagulation factors. -!- Formed from protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin, or by serine endopeptidases present in several snake venoms. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P04070 |
PROC_HUMAN
Homo sapiens
Vitamin K-dependent protein C
|
PDB Structure
| PDB | 1AUT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The 2.8 A crystal structure of Gla-domainless activated protein C.
EMBO J.
|
