CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.20 | Peptidase C15, pyroglutamyl peptidase I-like |
Domain Context
CATH Clusters
| Superfamily | Peptidase C15, pyroglutamyl peptidase I-like |
| Functional Family | Pyrrolidone-carboxylate peptidase |
Enzyme Information
| 3.4.19.3 |
Pyroglutamyl-peptidase I.
based on mapping to UniProt P46107
Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.
-!- Removes 5-oxoproline from various penultimate amino acid residues except L-proline. -!- Inhibited by thiol-blocking reagents. -!- Belongs to peptidase family C15. -!- Formerly EC 3.4.11.8.
|
UniProtKB Entries (1)
| P46107 |
PCP_BACAM
Bacillus amyloliquefaciens
Pyrrolidone-carboxylate peptidase
|
PDB Structure
| PDB | 1AUG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of pyroglutamyl peptidase I from Bacillus amyloliquefaciens reveals a new structure for a cysteine protease.
Structure Fold.Des.
|
