CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.33 | M1 Pyruvate Kinase; Domain 3 |
|
2.40.33.10 | PK beta-barrel domain-like |
Domain Context
CATH Clusters
| Superfamily | PK beta-barrel domain-like |
| Functional Family |
Enzyme Information
| 2.7.1.40 |
Pyruvate kinase.
based on mapping to UniProt P11974
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
|
UniProtKB Entries (1)
| P11974 |
KPYM_RABIT
Oryctolagus cuniculus
Pyruvate kinase PKM
|
PDB Structure
| PDB | 1AQF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ligand-induced domain movement in pyruvate kinase: structure of the enzyme from rabbit muscle with Mg2+, K+, and L-phospholactate at 2.7 A resolution.
Arch.Biochem.Biophys.
|
