CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.16 | Endonuclease - Pi-scei; Chain A, domain 1 |
|
2.170.16.10 | Hedgehog/Intein (Hint) domain |
Domain Context
CATH Clusters
| Superfamily | Hedgehog/Intein (Hint) domain |
| Functional Family |
Enzyme Information
| 5.6.2.3 |
DNA topoisomerase (ATP-hydrolyzing).
based on mapping to UniProt P72065
ATP-dependent breakage, passage and rejoining of double-stranded DNA.
-!- The enzyme can introduce negative superhelical turns into double- stranded circular DNA. -!- One unit has nicking-closing activity, and another catalyzes super- twisting and hydrolysis of ATP (cf. EC 5.6.2.2). -!- Formerly EC 5.99.1.3.
|
UniProtKB Entries (1)
| P72065 |
GYRA_MYCXE
Mycobacterium xenopi
DNA gyrase subunit A
|
PDB Structure
| PDB | 1AM2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing.
Nat.Struct.Biol.
|