CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Calcium/calmodulin-dependent protein kinase type 1

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q63450
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q63450
KCC1A_RAT
Rattus norvegicus
Calcium/calmodulin-dependent protein kinase type 1

PDB Structure

PDB 1A06
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Goldberg, J., Nairn, A.C., Kuriyan, J.
Cell(Cambridge,Mass.)
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