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CATH Superfamily 3.30.1230.20

Ribosomal protein S21

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ribosomal protein S21

This entry represents the ribosomal protein S21 (S21e) found in the small subunit (40S) of the ribosome. It exhibits a 2-layer alpha/beta sandwich fold with 2 alpha-helices and 2 beta-sheets.

S21 has been characterised in Drosophila (RpS21) and was found to bind to native 40S ribosomal subunits in a salt-labile association. It is absent from polysomes, indicating that it acts as a translation initiation factor rather than as a core ribosomal protein. RpS21 can interact strongly with P40, a ribosomal peripheral protein encoded by the stubarista(sta) gene PMID:10022917.

INTERPRO:IPR038579, PFAM:PF01249,DOI:10.1128/MCB.19.3.2308

GO Diversity

Unique GO annotations
30 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1472 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 66
Domain clusters (>95% seq id): 9
Domain clusters (>35% seq id): 2
Unique PDBs: 66
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 16
Function
Unique EC:
Unique GO: 30
Taxonomy
Unique Species: 1472