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Adenosine deaminase, putative, glycine betaine catabolic process, intracellular, Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate., growth cone, semaphorin-plexin signaling pathway, amidase activity, Enamidase., enamidase activity, 3,4-dihydroxybenzoate catabolic process, Saccharomyces cerevisiae YJM789, Phosphotriesterase variant PTE-R3, Sphingobium fuliginis, Putative 4-oxalomesaconate hydratase, Entamoeba histolytica, azurophil granule lumen, Dihydropyrimidinase-related protein 5, Sphingobium sp. SYK-6, -!- This bacterial enzyme is involved in degradation of the herbicide atrazine. -!- It can hydrolyze other N-substituted amino dihydroxy-s-triazine molecules, and prefers substrates with linear N-alkyl groups to those with branched alkyl groups. -!- Formerly EC 3.5.99.4., N-isopropylammelide isopropyl amidohydrolase, Adenine + H(2)O = hypoxanthine + NH(3)., Listeria monocytogenes EGD-e, Carboxylic ester hydrolases., Exoribonucleases producing 5'-phosphomonoesters., RNA phosphodiester bond hydrolysis, response to hydrogen peroxide, DNA polymerase III subunit alpha, tRNA 5'-leader removal, N-acetylglucosamine-6-phosphate deacetylase, protein homotetramerization, Klebsiella aerogenes, -!- Also acts on 5-methylcytosine., Cytosine deaminase, Phosphotriesterase variant PTE-R6, Uracil-5-carboxylate decarboxylase, 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, Aspergillus niger CBS 513.88, Aspartate transcarbamylase. ATCase. Carbamylaspartotranskinase., nuclear matrix, Urease., negative regulation of thymocyte apoptotic process, placenta development, xanthine biosynthetic process, adenosine catabolic process, embryonic digestive tract development, negative regulation of mature B cell apoptotic process, negative regulation of mucus secretion, cell surface, external side of plasma membrane, Blr3880 protein, Bradyrhizobium diazoefficiens USDA 110, Putative phophotriesterase, Brucella abortus 2308, Rhizobium sp. MTP-10005, Adenosine deaminase., Bos taurus, -!- Membrane bound, with broad specificity. -!- Abundant in the kidney cortex. -!- Inhibited by bestatin and cilastatin. -!- Belongs to peptidase family M19. -!- Formerly EC 3.4.3.1, EC 3.4.3.2, EC 3.4.3.6, EC 3.4.13.1, EC 3.4.13.2, EC 3.4.13.8, EC 3.4.13.11 and EC 3.4.13.15., negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, Allantoinase, cellular protein metabolic process, Escherichia coli ATCC 8739, Aspergillus niger ATCC 1015, -!- The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. -!- The enzyme has similar activity with ribonucleoside and 2'-deoxyribonucleoside 3',5'-bisphosphates, but shows no activity with nucleoside 2',5'-bisphosphates (cf. EC 3.1.3.7)., Brevundimonas diminuta, Bifidobacterium adolescentis ATCC 15703, Klebsiella pneumoniae 30660/NJST258_1, Omega peptidases., phosphoric ester hydrolase activity, 1,4-lactonase activity, AFL deaminase. Aminofutalosine deaminase., Aminodeoxyfutalosine deaminase, D-glucuronate isomerase. Uronate isomerase. Uronic acid isomerase. Uronic isomerase., Uronate isomerase, Putative dipeptidase, Molinate hydrolase, Adenine deaminase., deoxyribonuclease activity, cytosine catabolic process, cytosine deaminase activity, isoguanine deaminase activity, Hydrolase, -!- The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC 3.5.4.28) and has some activity against adenosine. -!- Adenosine-5-monophosphate (AMP) and S-adenosyl-L-methionine (SAM) are not substrates. -!- Formerly EC 3.5.4.n1., S-adenosylhomocysteine deaminase., -!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49., ochratoxin A catabolic process, -!- The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides. -!- The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length. -!- The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate. -!- The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate. -!- The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit. -!- The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. -!- Cf. EC 6.3.4.16. -!- Formerly EC 2.7.2.9., nucleoplasm, Pseudomonas aeruginosa PAO1, Urea + H(2)O = CO(2) + 2 NH(3)., Paraburkholderia phytofirmans PsJN, lactonohydrolase activity, Plasmodium yoelii yoelii, Alcaligenes faecalis, N-acyl-D-amino acid + H(2)O = a carboxylate + D-amino acid., Phenylurea hydrolase B, Pseudomonas sp. ADP, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, picolinic acid biosynthetic process, Adenosine aminohydrolase., Dehydropeptidase I. DPH I. Microsomal dipeptidase. Renal dipeptidase., extracellular exosome, homocysteine metabolic process, negative regulation of apoptotic process, nucleus, Agrobacterium tumefaciens, endocytosis, signal transduction, Hydrolysis of Xaa-|-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro., Archaeoglobus fulgidus DSM 4304, Nucleoside 3',5'-bisphosphate + H(2)O = nucleoside 5'-phosphate + phosphate., Phosphotriesterase homology protein, AMP deaminase., integral component of mitochondrial outer membrane, response to abscisic acid, Nitratiruptor sp. SB155-2, purine nucleotide salvage, Dictyostelium discoideum, Mycobacterium tuberculosis H37Rv, 'de novo' pyrimidine nucleobase biosynthetic process, 6-oxo-1,4,5,6-tetrahydronicotinate + 2 H(2)O = 2-formylglutarate + NH(3)., Eubacterium barkeri, DNA nucleotidyltransferase (DNA-directed). DNA-dependent DNA polymerase., DNA-directed DNA polymerase., Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)., N-acyl-D-glutamate deacylase, Phenylhydantoinase, Aminodeoxyfutalosine deaminase., Burkholderia ambifaria AMMD, Resiniferatoxin-binding, phosphotriesterase-related protein, L-histidinol phosphate + H(2)O = L-histidinol + phosphate., Tyrosine-protein phosphatase CpsB, purine nucleotide catabolic process, dendrite, DNA polymerase III PolC-type, Lactobacillus paracasei ATCC 334, Uncharacterized metal-dependent hydrolase YcfH, Phosphotriesterase variant PTE-revR6, Pseudomonas aeruginosa, Planctopirus limnophila DSM 3776, Phosphotriesterase variant PTE-R2, Pyrococcus horikoshii OT3, Phosphotriesterase variant PTE-R1, -!- Essential for tRNA processing; generates 5'-termini of mature tRNA molecules., Thermus thermophilus HB8, Phosphoric monoester hydrolases., -!- Also acts on dihydrothymine and hydantoin., 5,6-dihydrouracil + H(2)O = 3-ureidopropanoate., D-hydantoinase/dihydropyrimidinase, Phosphotriesterase variant PTE-revR12, Mycoplasma synoviae 53, In cyclic amides., Amidohydrolase 2, Novosphingobium aromaticivorans DSM 12444, Burkholderia multivorans ATCC 17616, Sporosarcina pasteurii, D-galactaro-1,5-lactone = D-galactaro-1,4-lactone., Sphingomonas paucimobilis, Aminocarboxymuconate-semialdehyde decarboxylase., Picolinic acid decarboxylase., -!- Formerly EC 3.5.1.80., N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate., adenine deaminase activity, cytosol, Urease subunit alpha, Gamma-resorcylate decarboxylase, Polaromonas sp. JS666, dATP catabolic process, in utero embryonic development, negative regulation of inflammatory response, positive regulation of T cell differentiation, positive regulation of T cell receptor signaling pathway, positive regulation of smooth muscle contraction, trophectodermal cell differentiation, T cell activation, Proteus mirabilis HI4320, Mg-dependent cytoplasmic DNase / RNase, Tyrosine-protein phosphatase YwqE, leukotriene metabolic process, Escherichia coli K-12, protein histidine kinase binding, Lactococcus lactis subsp. lactis Il1403, Vibrio cholerae O1 biovar El Tor str. N16961, Imidazolonepropionase, Imidazolonepropionase., -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2., Protein-tyrosine-phosphatase., GAH. Guanase. Guanine aminase., guanine deaminase activity, 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = (1E)-4-oxobut-1-ene-1,2,4- tricarboxylate., 2-pyrone-4,6-dicarboxylate lactonase activity, Oleispira antarctica, Cajanus cajan, 3',5'-nucleoside bisphosphate phosphatase., Putative deoxyribonuclease TATDN1, iron ion binding, Deacetylase Atu3266, bacterial-type flagellum-dependent swarming motility, negative regulation of neuron projection development, Paenarthrobacter aurescens, 5-methylthioadenosine/S-adenosylhomocysteine deaminase, S-adenosyl-L-homocysteine + H(2)O = S-inosyl-L-homocysteine + NH(3)., DNA polymerase III, core complex, DNA-directed DNA polymerase activity, Hydrolase TatD family protein, Aquifex aeolicus VF5, Bacillus subtilis subsp. subtilis str. 168, Rhodopseudomonas palustris CGA009, -!- Also converts D-galacturonate to D-tagaturonate., Dihydropyrimidinase., Gulosibacter molinativorax, Urease, Adenine deaminase, 3'-5'-exoribonuclease activity, Exodeoxyribonucleases producing 5'-phosphomonoesters., Thermus sp., ribonuclease P activity, lung development, negative regulation of penile erection, regulation of T cell differentiation, N-acetylglucosamine-6-phosphate deacetylase activity, N-acetylglucosamine-6-phosphate deacetylase., D-hydantoinase, -!- Has a wide specificity; hydrolyzes N-acyl derivative of neutral D-amino acids. -!- Used in separating D- and L-amino acids., Agrobacterium fabrum str. C58, -!- The product rearranges non-enzymically to picolinate., regulation of 'de novo' NAD biosynthetic process from tryptophan, Dihydropyrimidinase-related protein 2, Acting on carbon-nitrogen bonds, other than peptide bonds., Geobacillus kaustophilus HTA426, Xaa-Pro dipeptidase., 2 ATP + L-glutamine + HCO(3)(-) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate., Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate., Carbamoyl-phosphate synthase (glutamine-hydrolyzing)., Peyer's patch development, germinal center B cell differentiation, inosine biosynthetic process, Dipeptidase 1, Membrane dipeptidase., modified amino acid binding, Parathion hydrolase, AMP + H(2)O = IMP + NH(3)., Dihydroorotase, Putative deoxyribonuclease TATDN3, uracil catabolic process, Geobacillus stearothermophilus 10, -!- The enzyme, found in several bacterial species, is part of the futalosine pathway for menaquinone biosynthesis., (S)-allantoin + H(2)O = allantoate., Bacillus halodurans C-125, neutrophil degranulation, Phosphotriesterase variant PTE-R8, N-formimidoyl-L-glutamate + H(2)O = N-formyl-L-glutamate + NH(3)., Uncharacterized metal-dependent hydrolase YjjV, Xanthomonas campestris pv. campestris str. ATCC 33913, 2-pyrone-4,6-dicarboxylic acid hydrolase, Dipeptidase, -!- The product is most likely the keto-form of 4-oxalmesaconate (shown). -!- It can be converted to the enol-form, 4-hydroxybuta-1,3-diene-1,2,4- trioate, either spontaneously or by EC 5.3.2.8., 2-pyrone-4,6-dicarbaxylate hydrolase, formimidoylglutamate deiminase activity, Plasmodium vivax Sal-1, Isoaspartyl dipeptidase, N-isopropylammelide isopropylaminohydrolase., Dihydropyrimidinase-related protein 1, filamin binding, negative regulation of actin filament binding, Bacillus anthracis, S-methyl-5'-thioadenosine deaminase., Pyrococcus furiosus DSM 3638, Lachancea kluyveri NRRL Y-12651, axon guidance, phosphoric diester hydrolase activity, Histidinol-phosphatase., Guanine + H(2)O = xanthine + NH(3)., Guanine deaminase., phosphoprotein binding, Cordyceps militaris CM01, 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate semialdehyde + CO(2)., protein oligomerization, Dihydropyrimidinase, D-glucuronate = D-fructuronate., Glucuronate isomerase., Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Canavalia ensiformis, Adenase. Adenine aminase., Dipeptidase AC, Enterococcus faecalis V583, Putative metal-dependent phosphoesterases (PHP family), In cyclic amidines., 5-carboxyvanillate decarboxylase, -!- Possibly thiol dependent. -!- Cytosolic from most animal tissues. -!- Belongs to peptidase family M24A. -!- Formerly EC 3.4.3.7., In linear amides., Aryldialkylphosphatase, Helicobacter mustelae 12198, Urease subunit beta, positive regulation of T cell activation, positive regulation of T cell differentiation in thymus, positive regulation of germinal center formation, Phosphotriesterase, putative, D-aminoacylase., N-acyl-D-amino-acid deacylase., Geobacillus stearothermophilus, Tetraodon nigroviridis, D-galactarolactone isomerase., Thermophilic reversible gamma-resorcylate decarboxylase, Adenosine deaminase, apical part of cell, metalloexopeptidase activity, xenobiotic metabolic process, nervous system development, dihydroorotase activity, Phosphotyrosine phosphatase. PTPase., neuronal cell body, Burkholderia cenocepacia J2315, Xaa-Pro dipeptidase, putative, Phosphotriesterase variant PTE-E2, pyrimidine nucleobase catabolic process, Lactobacillus plantarum WCFS1, aryldialkylphosphatase activity, -!- Cf. EC 3.5.4.17., intracellular membrane-bounded organelle, Bacteroides vulgatus ATCC 8482, Staphylococcus aureus subsp. aureus Mu50, purine-containing compound salvage, response to hypoxia, Formimidoylglutamate deiminase., Xaa-Pro Dipeptidase, choline catabolic process, Phosphotriesterase variant PTE-R18, Acting on ester bonds., midbody, S-adenosylhomocysteine deaminase activity, Bacillus sp. AR9, Metal-dependent hydrolase, Brucella suis 1330, L-hydantoinase, protein homodimerization activity, proteoglycan binding, beta-aspartyl-peptidase activity, Hydantoinase., N-isopropylammelide + H(2)O = cyanuric acid + isopropylamine., Metarhizium robertsii ARSEF 23, 3'-5' ssDNA/RNA exonuclease TatD, DNA catabolic process, exonucleolytic, Endodeoxyribonucleases producing 5'-phosphomonoesters., single-stranded DNA 3'-5' exodeoxyribonuclease activity, Cytosine + H(2)O = uracil + NH(3)., Cytosine deaminase., 5-methylthioadenosine deaminase. MTA deaminase., Histidinol phosphatase, ribonuclease P complex, Ribonuclease P protein component 3, Amidohydrolase, Phosphotriesterase variant PTE-E1, -!- Involved in the degradation of the herbicide atrazine, 2-chloro-4- (ethylamino)-6-(isopropylamino)-1,3,5-triazine, in bacteria., -!- The enzyme, characterized from the bacterium Agrobacterium fabrum strain C58, belongs to the amidohydrolase superfamily. -!- It participates in the degradation of D-galacturonate., Brevibacillus agri, adenosine deaminase activity, negative regulation of leukocyte migration, positive regulation of calcium-mediated signaling, Deinococcus radiodurans R1, Phosphotriesterase, dihydropyrimidinase activity, Carbamoyl phosphate synthetase. Carbamoyl-phosphate synthetase (glutamine-hydrolyzing). Carbamoylphosphate synthetase II. Carbamyl phosphate synthetase (glutamine). CPS. GD-CPSase. Glutamine-dependent carbamoyl-phosphate synthase. Glutamine-dependent carbamyl phosphate synthetase., carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, negative regulation of adenosine receptor signaling pathway, regulation of cell-cell adhesion mediated by integrin, Formiminoglutamate deiminase., Sinorhizobium meliloti, Pseudomonas putida KT2440, dipeptidase activity, glutathione metabolic process, negative regulation of cell migration, A-esterase. Aryltriphosphatase. Paraoxon hydrolase. Paraoxonase. Phosphotriesterase., Aryldialkylphosphatase., Carbamoylaspartic dehydrase. DHOase., Dihydroorotase., adenosine receptor binding, extracellular region, Caulobacter crescentus CB15, Ralstonia pickettii, Histidinol-phosphatase, Guanine deaminase, 4(5)-imidazolone-5(4)-propionic acid hydrolase. Imidazolone propionic acid hydrolase. Imidazolone-5-propionate hydrolase., PvdM, 2-pyrone-4,6-dicarboxylate lactonase., Vulcanisaeta moutnovskia 768-28, Organophosphorus hydrolase, zinc ion binding, AMP deaminase, embryo development ending in seed dormancy, histidine catabolic process, Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor., Ribonuclease P., Thermococcus kodakarensis KOD1, DNA polymerase beta family (X family), Burkholderia lata, Alteromonas macleodii, Phosphotriesterase variant PTE-R0, Staphylococcus aureus subsp. aureus MW2, Triazine hydrolase, -!- Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32., Enamidase, Chromobacterium violaceum ATCC 12472, N-acyl-D-glutamate amidohydrolase., 6-amino-6-deoxyfutalosine + H(2)O = futalosine + NH(3)., metal ion binding, Phosphotriesterase variant PTE-R22, Atrazine chlorohydrolase, D-galactarolactone isomerase, aminocarboxymuconate-semialdehyde decarboxylase activity, tryptophan catabolic process, Streptomyces coelicolor A3(2), Predicted amidohodrolase (Dihydroorotase family), Paenarthrobacter aurescens TC1, Lmo2462 protein, Rhodobacter sphaeroides 2.4.1, Deacetylase EF_0837, Pseudomonas fluorescens, Gamma-peptidase. Imidodipeptidase. Peptidase D. Prolidase. Proline dipeptidase. X-Pro dipeptidase., Aspartate carbamoyltransferase., aspartate carbamoyltransferase activity, membrane, pyrimidine nucleoside biosynthetic process, Thermotoga maritima MSB8, N-acetylneuraminate catabolic process, (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate., cytoplasm, deoxyadenosine catabolic process, lung alveolus development, positive regulation of B cell proliferation, positive regulation of alpha-beta T cell differentiation, positive regulation of heart rate, identical protein binding, Porphyromonas gingivalis W83, Helicobacter pylori 26695, Predicted metal-dependent hydrolase of the TIM-barrel fold, antibiotic metabolic process, cellular response to drug, -!- Acts on organophosphorus compounds (such as paraoxon) including esters of phosphonic and phosphinic acids. -!- Inhibited by chelating agents. -!- Previously regarded as identical with EC 3.1.1.2., plasma membrane, (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + H(2)O = N-formimidoyl-L-glutamate + H(+)., Streptococcus pneumoniae TIGR4, Dihydropyrimidinase-related protein 3, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Thermus aquaticus, 3'-5'-exonuclease, pyrimidine nucleoside catabolic process, 3',5'-nucleoside bisphosphate phosphatase, 3',5'-nucleotide bisphosphate phosphatase activity, dephosphorylation, manganese ion binding, allantoin assimilation pathway, allantoinase activity, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Putative deoxyribonuclease YcfH, Adenosine deaminase CECR1, extracellular space, Allantoinase., Lactobacillus acidophilus NCFM, Probable phosphatase YcdX, Hydrolases., Yersinia enterocolitica W22703, cofactor catabolic process, S-methyl-5'-thioadenosine + H(2)O = S-methyl-5'-thioinosine + NH(3)., Adenine deaminase 2, N-acyl-D-glutamate + H(2)O = a carboxylate + D-glutamate., N-acyl-D-glutamate deacylase., 4-oxalomesaconate hydratase, negative regulation of quinolinate biosynthetic process, Bordetella bronchiseptica RB50, N-acetylglucosamine catabolic process, Clostridium acetobutylicum ATCC 824, Cytosine/guanine deaminase related protein, Cytosine aminohydrolase., ferrous iron binding, Putative amidohydrolase, CAD protein, enzyme binding, Sulfolobus solfataricus P2, Uncharacterized protein, Mus musculus, hypoxanthine biosynthetic process, liver development, D-aminoacylase, Atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5- triazine + HCl., Atrazine chlorohydrolase., Mycobacterium brisbanense, An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol., Adenosine + H(2)O = inosine + NH(3)., Homo sapiens, Hydrolysis of dipeptides., cell junction, cellular lactam catabolic process, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, metallodipeptidase activity, protein binding, nucleobase-containing compound metabolic process