Search CATH

L-glutamate 1-carboxy-lyase., glutamate decarboxylase activity, neurotransmitter secretion, Leukocyte immunoglobulin-like receptor subfamily A member 3, negative regulation of alpha-beta T cell proliferation, rhabdomere, Cell surface protein, lacrimal gland development, odontogenesis, prostate epithelial cord elongation, synaptic vesicle transport, Murine cytomegalovirus (strain K181), B- and T-lymphocyte attenuator, cellular hypotonic response, lymphangiogenesis, commissural neuron axon guidance, negative regulation of immune response to tumor cell, negative regulation of immunological synapse formation, -!- Acts on starch and related polysaccharides and oligosaccharides. -!- The product is alpha-maltose; cf. EC 3.2.1.2., Maltogenic alpha-amylase., CD48 antigen, V1-22 protein, -!- Also acts on sn-glycero-3-phosphoethanolamine., activation of GTPase activity, Twitchin, behavioral response to nicotine, peptidyl-threonine phosphorylation, positive regulation of striated muscle contraction, Endo-1,4-beta-xylanase., Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans., Carcinoembryonic antigen-related cell adhesion molecule 15, positive regulation of actin filament polymerization, Dpr-interacting protein alpha, isoform A, immune response to tumor cell, regulation of JNK cascade, follicular dendritic cell differentiation, Corynebacterium diphtheriae NCTC 13129, advanced glycation end-product binding, protein localization to membrane, Melibiase., Next to BRCA1 gene 1 protein, HLA class I histocompatibility antigen, Cw-4 alpha chain, H-2 class I histocompatibility antigen, D-37 alpha chain, Cycloisomaltooligosaccharide glucanotransferase, Type-1 fimbrial protein, A chain, positive regulation of bone mineralization, HADV29S1, beta-amyloid binding, negative regulation of protein binding, positive regulation of endocytic recycling, positive regulation of protein catabolic process, protein targeting to Golgi, Putative fimbrial subunit, Interleukin-1 receptor-like 1, Yersinia pseudotuberculosis IP 32953, MHC class II protein complex assembly, Neuroplastin, positive regulation of long-term neuronal synaptic plasticity, Escherichia coli F18+, FimH protein, response to vitamin D, Down syndrome cell adhesion molecule-like protein 1, -!- Variants of this enzyme have been found in species of Bacillus including B.subtilis, B.amyloliquefaciens, B.megaterium, B.mesentericus, B.cereus and B.stearothermophilus. -!- Belongs to peptidase family M4. -!- Formerly EC 3.4.24.4., V-set domain-containing T-cell activation inhibitor 1, polysaccharide binding, Leptospira interrogans serovar Pomona, regulation of protein localization to cell surface, Aequorea victoria, Ig heavy chain V region 1B43, Myosin-binding protein C, cardiac-type, cardiac myofibril, Immunoglobulin heavy variable 3-33, ErbB-2 class receptor binding, Erbin, nuclear speck, branching morphogenesis of an epithelial tube, platelet-derived growth factor binding, amine metabolic process, Lin-12 And Glp-1 phenotype, germ-line stem cell division, Immunoblobulin G1 Fab heavy chain variable region, Interleukin-7 receptor subunit alpha, Coxsackievirus and adenovirus receptor homolog, heart development, interleukin-28 receptor complex, Periplasmic chaperone, Down syndrome cell adhesion molecule 1, isoform G, H-2 class I histocompatibility antigen, D-D alpha chain, Outer capsid protein lambda-2, S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m(7)G(5')pppR-RNA., regulation of lymphocyte apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of protein kinase B signaling, Ig kappa chain V-VI region J539, Collagenase, Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305, B-cell antigen receptor complex-associated protein beta chain, positive regulation of transcription of Notch receptor target, neuronal cell body membrane, activation of NF-kappaB-inducing kinase activity, Endo-beta-N-acetylglucosaminidase, HLA class I histocompatibility antigen, B-46 alpha chain, Immunoglobulin kappa variable 3-20, Glucuronidase, apoptotic signaling pathway, keratinocyte development, ferritin receptor activity, Alpha-1,4-D-endopolygalacturonic acid lyase. Endo-alpha-1,4-polygalacturonic acid lyase. Endogalacturonate transeliminase. Endopectin methyltranseliminase. Pectate transeliminase. Pectic acid lyase. Pectic acid transeliminase. Pectic lyase. Pectin trans-eliminase. PGA lyase. Polygalacturonate lyase. Polygalacturonic acid lyase. Polygalacturonic acid trans-eliminase. Polygalacturonic transeliminase. PPase-N., negative regulation of autophagy, artery morphogenesis, atrioventricular canal development, epithelial to mesenchymal transition, hair follicle maturation, positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment, [Bacillus] clarkii, Hepatitis A virus cellular receptor 1, motile cilium, negative regulation of apoptotic cell clearance, Glucan 1,4-alpha-glucosidase., positive regulation of humoral immune response, Exo-alpha-sialidase., Cell adhesion molecule 3, Interferon alpha/beta receptor 1, monocyte differentiation, Chitinase 60, Novel antigen receptor, V_segment translation product, Dscam, interleukin-2 biosynthetic process, Fab4201 heavy chain, regulation of signal transduction by p53 class mediator, regulation of cell migration, wound healing, spreading of cells, Fc-gamma receptor I complex binding, GTPase binding, Amyloid beta A4 protein, negative regulation of canonical Wnt signaling pathway, negative regulation of dendritic spine maintenance, negative regulation of long-term synaptic potentiation, neuron apoptotic process, regulation of NMDA receptor activity, regulation of synaptic plasticity, response to yeast, Orectolobus maculatus, Natural cytotoxicity triggering receptor 3, immune response-activating cell surface receptor signaling pathway, Contactin-1, SbsB protein, negative regulation of regulatory T cell differentiation, CD4 receptor binding, HLA class II histocompatibility antigen, DRB1-4 beta chain, inflammatory response to antigenic stimulus, Escherichia coli CFT073, T-cell receptor delta chain C region, transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding, Human nkt tcr alpha chain, MHC class II antigen, Ephrin type-B receptor 4, ephrin receptor activity, negative regulation of MAP kinase activity, phosphatidylethanolamine binding, Leucine-rich repeats and immunoglobulin-like domains protein 1, CD8-positive, alpha-beta T cell activation, positive regulation of TRAIL production, positive regulation of natural killer cell mediated immunity, negative regulation of interleukin-1 production, negative regulation of interleukin-2 production, negative regulation of lipid biosynthetic process, negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, positive regulation by host of viral process, positive regulation of NFAT protein import into nucleus, regulation of blood vessel remodeling, regulation of endothelial cell differentiation, regulation of epidermal growth factor receptor signaling pathway, virus receptor activity, Sialoadhesin, negative regulation of translation, Contactin-5, natural killer cell mediated cytotoxicity, Cell surface glycoprotein CD200 receptor 4, cell-cell contact zone, cilium organization, Immunoglobulin heavy constant gamma 2, microtubule cytoskeleton organization, Receptor-type tyrosine-protein phosphatase F, CDw150, Vibrio harveyi, thermotaxis, positive regulation of T cell tolerance induction, Intercellular adhesion molecule 2, cell-substrate junction assembly, Ig lambda-2 chain C region, axon midline choice point recognition, salivary gland boundary specification, A beta-D-glucuronoside + H(2)O = D-glucuronate + an alcohol., phosphatidylinositol biosynthetic process, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, clustering of voltage-gated sodium channels, Kin of irre, isoform A, filtration diaphragm assembly, HLA class II histocompatibility antigen, DQ beta 1 chain, Anti-F4+ETEC bacteria VHH variable region, positive regulation of antigen processing and presentation, Ig kappa chain C region, B allele, Ig lambda-1 chain V region S43, Photobacterium profundum SS9, Putative endoglucanase-related protein, Programmed cell death protein 1, susceptibility to T cell mediated cytotoxicity, R7 cell development, photoreceptor cell morphogenesis, HLA class II histocompatibility antigen, DO beta chain, positive regulation of pinocytosis, compound eye development, Tie signaling pathway, chemotaxis, germ cell development, immature B cell differentiation, megakaryocyte development, melanocyte adhesion, histone deacetylase binding, nuclear chromatin, nucleotide-binding oligomerization domain containing 2 signaling pathway, phosphate ion binding, positive regulation of NIK/NF-kappaB signaling, transcription factor binding, transcription regulatory region DNA binding, transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding, TRIF-dependent toll-like receptor signaling pathway, macrophage apoptotic process, Interferon regulatory factor 7, negative regulation of macrophage apoptotic process, positive regulation of interferon-alpha production, positive regulation of T cell differentiation, negative regulation of GTPase activity, transforming growth factor beta receptor signaling pathway, C-terminal protein lipidation, Roundabout homolog 2, activation of MAPKK activity, peptidyl-tyrosine autophosphorylation, positive regulation of neuron projection development, Interleukin-10 receptor subunit alpha, cell maturation, hepatic immune response, T cell receptor alpha variable 27, Interleukin-18 receptor 1, Putative polysaccharide lyase family 11 protein, regulation of protein complex assembly, Ig mu chain C region, IgG binding, Hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate., lysosomal lumen, Intercellular adhesion molecule 1, receptor-mediated virion attachment to host cell, Periplasmid chaperone PapD protein, Interleukin-4 receptor subunit alpha, T-helper cell differentiation, interleukin-23 complex, positive regulation of natural killer cell proliferation, vitamin D3 metabolic process, Fibronectin type-III domain-containing protein 3A, mast cell chemotaxis, mast cell differentiation, sarcolemma, HLA class I histocompatibility antigen, B-57 alpha chain, activation of signaling protein activity involved in unfolded protein response, positive regulation by host of viral release from host cell, protein heterodimerization activity, Gallus gallus, outer membrane, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding, endosome lumen, pyruvate metabolic process, cytokine binding, forebrain neuron differentiation, macrophage colony-stimulating factor signaling pathway, phosphatidylinositol metabolic process, vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, Butyrophilin subfamily 3 member A1, activated T cell proliferation, HLA class II histocompatibility antigen, DR beta 3 chain, integrin-mediated signaling pathway, Limit dextrinase, ColH protein, Hathewaya histolytica, Histidine protein kinase. HK1. Protein histidine kinase. Protein kinase. Protein kinase (histidine)., Cell surface glycoprotein CD200 receptor 1, intracellular vesicle, fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development, negative regulation of fibroblast growth factor production, outer ear morphogenesis, positive regulation of mesenchymal cell proliferation, HLA class II histocompatibility antigen, DRB1-3 chain, Golgi lumen, Neopullulanase 1, High affinity immunoglobulin gamma Fc receptor I, Carcinoembryonic antigen-related cell adhesion molecule 6, Bacillus circulans, MHC class 1 protein, Chitinase, SH2 domain binding, negative regulation of CD8-positive, alpha-beta T cell activation, negative regulation of cell cycle, negative regulation of endocytosis, positive regulation of defense response to virus by host, -!- Converts amylose into amylopectin. -!- The description (official name) requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme. -!- The latter has frequently been termed Q-enzyme., 1,4-alpha-glucan branching enzyme GlgB, Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain., HLA class I histocompatibility antigen, A-1 alpha chain, synapse assembly, stem cell population maintenance, protein ubiquitination, Chaperone protein FocC, Fibrinoligase. Glutaminylpeptide gamma-glutamyltransferase. Polyamine transglutaminase. TGase. Transglutaminase., Protein-glutamine gamma-glutamyltransferase., keratinocyte differentiation, protein tetramerization, endoplasmic reticulum-Golgi intermediate compartment, integrin activation, post-translational protein modification, MAPK cascade, IGH@ protein, telethonin binding, antigen processing and presentation, endogenous lipid antigen via MHC class Ib, HLA class II histocompatibility antigen, DM alpha chain, Cellulomonas fimi, Deinococcus radiodurans R1, Triggering receptor expressed on myeloid cells 1, neutrophil extravasation, IgA receptor activity, positive regulation of neutrophil apoptotic process, Titin, cardiac muscle contraction, detection of muscle stretch, striated muscle contraction, structural molecule activity conferring elasticity, calcium-mediated signaling using intracellular calcium source, apical plasma membrane, neuron projection development, TRAV14-3, Hi113 protein, Lama glama, IgG receptor FcRn large subunit p51, multicellular organism metabolic process, Naja kaouthia, positive regulation of focal adhesion assembly, positive regulation of mitochondrial fission, transmembrane receptor protein tyrosine kinase signaling pathway, transmembrane receptor protein tyrosine phosphatase activity, Integrin beta-4, cell motility, C5L2 anaphylatoxin chemotactic receptor binding, Complement C3, negative regulation of transcription, DNA-templated, axon guidance receptor activity, detection of molecule of bacterial origin, neuron projection, antigen processing and presentation, exogenous lipid antigen via MHC class Ib, positive regulation of NK T cell activation, polytene chromosome, sensory organ precursor cell fate determination, Glutamate decarboxylase 2, L-glutamate = 4-aminobutanoate + CO(2)., Butyrophilin subfamily 1 member A1, cartilage development, neurotrophin receptor activity, Escherichia coli K-12, membrane, early endosome, glycoprotein binding, positive regulation of monocyte differentiation, phagocytosis, recognition, positive regulation of phagocytosis, -!- Cyclomaltodextrins (Schardinger dextrins) of various sizes (6, 7, 8, etc. glucose units) are formed reversibly from starch and similar substrates. -!- Also disproportionates linear maltodextrins without cyclizing (cf. EC 2.4.1.25)., Thermoanaerobacterium thermosulfurigenes, Arg-gingipain. Argingipain. Gingipain-1., Gingipain R., Hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1., calcium-dependent cysteine-type endopeptidase activity, antigen processing and presentation of endogenous peptide antigen via MHC class I, regulation of complement activation, response to retinoic acid, LigB-like protein, extracellular exosome, extracellular space, protein processing, lysosome, peptide antigen assembly with MHC class II protein complex, Leukocyte immunoglobulin-like receptor subfamily B member 4, Immunoglobulin kappa constant, DNA binding, antigen processing and presentation, oncostatin-M receptor complex, positive regulation of tyrosine phosphorylation of STAT protein, Igh protein, aging, phosphatase binding, regulation of sensory perception of pain, response to cocaine, thalamus development, apicolateral plasma membrane, embryonic cranial skeleton morphogenesis, fibroblast growth factor-activated receptor activity, nucleoplasm, phosphatidylinositol-4,5-bisphosphate 3-kinase activity, Interleukin-1 receptor type 1, interleukin-1-mediated signaling pathway, Bacillus cereus, Beta-amylase, TAP binding, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, Invasin, HLA class II histocompatibility antigen, DO alpha chain, positive regulation of cellular protein localization, interleukin-3 receptor activity, MHC class II HLA-DQ-alpha chain, CD8 alpha chain, post-Golgi vesicle-mediated transport, protein targeting to lysosome, [Myosin-light-chain] kinase. Calcium/calmodulin-dependent myosin light chain kinase. MLCK. MLCkase. Myosin kinase. Myosin light chain kinase. Myosin light chain protein kinase. Myosin light-chain kinase. Myosin light-chain kinase (phosphorylating). Smooth-muscle-myosin-light-chain kinase., aorta smooth muscle tissue morphogenesis, Schwann cell development, dystroglycan binding, dystroglycan complex, maternal process involved in female pregnancy, Bacillolysin., Dyslexia-associated protein KIAA0319, Kelch domain-containing protein, cochlea development, positive regulation of synaptic growth at neuromuscular junction, Endo-beta-N-acetylglucosaminidase D, Hereditary hemochromatosis protein, negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, negative regulation of receptor activity, transferrin receptor binding, Human alphaherpesvirus 1, Geobacter metallireducens GS-15, Minor pilin subunit PapF, -!- Also readily hydrolyzes amylopectin. -!- Differs from EC 3.2.1.41 and EC 3.2.1.142 by its inability to hydrolyze pullulan, and by limited action on alpha-limit dextrins. -!- Maltose is the smallest sugar it can release from an alpha-(1->6)- linkage., apoptotic DNA fragmentation, release from viral latency, Clostridium perfringens ATCC 13124, Glycoside hydrolase O-GlcNAcase. O-GlcNAc hydrolase. O-GlcNAcase. OGA., excitatory synapse, fibroblast growth factor receptor signaling pathway involved in mammary gland specification, lateral sprouting from an epithelium, mesenchymal cell proliferation involved in lung development, morphogenesis of embryonic epithelium, outflow tract septum morphogenesis, positive regulation of Wnt signaling pathway, prostate gland morphogenesis, regulation of smooth muscle cell differentiation, Hepatitis A virus cellular receptor 2 homolog, T-cell costimulatory molecule CD28, Myotilin, negative regulation of neutrophil activation, Glucan 1,4-alpha-maltohydrolase., Fervidobacterium pennivorans, Tenascin-R, T-cell receptor gamma chain C region DFL12, SNF1 protein kinase subunit beta-2, invasive growth in response to glucose limitation, Ephrin type-A receptor 2, regulation of cell adhesion, Natural killer cell receptor 2B4, integral component of external side of plasma membrane, positive regulation of transcription from RNA polymerase II promoter in response to hypoxia, negative regulation of tolerance induction, adult locomotory behavior, -!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn., Protein turtle homolog A, -!- Also hydrolyzes alpha-D-fucosides., Alpha-galactosidase., HLA class I histocompatibility antigen, Cw-3 alpha chain, cell projection organization, Ephrin type-A receptor 8, H2-T22 protein, Cytotoxic Tcell receptor, R2 protein, CD276 antigen, Grass carp reovirus, Clara cell differentiation, dorsal aorta morphogenesis, heart looping, negative regulation of cell differentiation, pituitary gland development, secondary heart field specification, Immunoglobulin heavy constant gamma 3, microtubule, 2L protein, positive regulation of stress fiber assembly, hexameric IgM immunoglobulin complex, Streptococcus pneumoniae R6, 1,4-beta-D-glucan glucanohydrolase. XEG. Xyloglucan endo-beta-1,4-glucanase. Xyloglucanase. Xyloglucanendohydrolase., mutualism, Ani2.3 TCR B chain, MHC class I polypeptide-related sequence A, cell-substrate adhesion, actin filament, iron ion import, Phosphoric monoester hydrolases., chloroplast stroma, Cytokine receptor-like factor 2, T-helper 2 cell cytokine production, Ginglymostoma cirratum, Trichoderma harzianum, positive regulation of dendrite development, platelet-derived growth factor-activated receptor activity, associative learning, positive regulation of response to endoplasmic reticulum stress, regulation of acetylcholine-gated cation channel activity, regulation of neuron projection development, T-cell immunoreceptor with Ig and ITIM domains, Human nkt tcr beta chain, Beta-glucosidase 1, Paired immunoglobulin-like type 2 receptor beta, compound eye retinal cell programmed cell death, Down syndrome cell adhesion molecule 1, isoform AU, Histocompatibility 2, T region locus 22, Glucans biosynthesis protein G, beta-glucan biosynthetic process, myosin binding, ERBB2 signaling pathway, hepatocyte growth factor-activated receptor activity, Pre T-cell antigen receptor alpha, positive regulation of interleukin-1 beta secretion, Beta-D-glucoside glucohydrolase, Leukocyte immunoglobulin-like receptor subfamily B member 2, regulation of DNA recombination, Glycoside hydrolase family 2, candidate beta-glycosidase, acrosomal vesicle, cell body, Neurofascin, Low affinity immunoglobulin gamma Fc region receptor III-A, Escherichia coli O139:H28 str. E24377A, negative regulation of pri-miRNA transcription from RNA polymerase II promoter, platelet activating factor receptor activity, HLA-B35, ubiquitin-protein transferase activity, Endoglucanase-related protein, Vibrio parahaemolyticus RIMD 2210633, Interleukin-20 receptor subunit beta, homeostasis of number of cells, T cell receptor beta variable 19, receptor-receptor interaction, H2-M beta 2, MHC class I antigen, negative regulation of cell adhesion, Interleukin-1 receptor accessory protein, fertilization, Vibrio cholerae M66-2, serine-type peptidase activity, H-2 class II histocompatibility antigen, A beta chain, intracellular, toxic substance binding, nervous system development, Low affinity immunoglobulin gamma Fc region receptor II-a, positive regulation of mast cell activation, Autographa californica nucleopolyhedrovirus, Cytotoxic T-lymphocyte protein 4, HLA class I histocompatibility antigen, B-7 alpha chain, regulation of dendritic cell differentiation, regulation of interleukin-6 production, -!- Reaction also occurs with beta-D-galactopyranosyl-(1->3)-N-acetyl-D- galactosamine as the substrate, giving N-acetyl-D-galactosamine as the product., CD1b3, Plexin-A2, Golgi stack, photoreceptor outer segment, Dextranase., positive regulation of chemokine secretion, Pullulanase, Rac GTPase binding, negative regulation of transcription from RNA polymerase I promoter, peptidase activator activity, neuron recognition, IgM heavy chain VDJ region, Sodium channel subunit beta-4, sodium ion transport, voltage-gated sodium channel activity, MHC class II HLA-DQ-beta-1, calcium-mediated signaling, wing disc pattern formation, Mus sp., lamellipodium, negative regulation of endothelial cell migration, nuclear body, CMRF35-like molecule 1, interleukin-4 receptor binding, Ig kappa chain V-V region K2, -!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. -!- This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions., HLA class I histocompatibility antigen, B-51 alpha chain, Sialidase, polymeric immunoglobulin receptor activity, membrane depolarization during action potential, positive regulation of sodium ion transport, glycosphingolipid metabolic process, spermatid development, stem cell differentiation, NF-kappaB binding, NF-kappaB p50/p65 complex, cellular response to nicotine, membrane protein intracellular domain proteolysis, positive regulation of T cell receptor signaling pathway, Contactin-2, membrane to membrane docking, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of negative chemotaxis, positive regulation of axonogenesis, brain-derived neurotrophic factor-activated receptor activity, nerve growth factor binding, Bos taurus, auditory receptor cell development, blood vessel morphogenesis, generation of neurons, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, regulation of phosphorus metabolic process, positive regulation of interleukin-6 production, regulation of cell morphogenesis, Ig heavy chain V region MOPC 21, Synaptogenesis protein syg-1, messenger ribonucleoprotein complex, regulation of epidermal cell differentiation, Netrin receptor DCC, negative regulation of collateral sprouting, negative regulation of dendrite development, T cell receptor beta variable 25-1, Cytokine receptor common subunit gamma, Hoc head outer capsid protein, chondroitin sulfate catabolic process, Set1C/COMPASS complex, Galactose oxidase., centrosome, Chaperone protein PapD, Anti-HIV-1 reverse transcriptase single-chain variable, Novel immune-type receptor 10, HLA class I histocompatibility antigen, alpha chain E, MHC class Ib protein complex, regulation of natural killer cell mediated immunity, Toll-like receptor binding, negative regulation of hepatocyte proliferation, negative regulation of osteoclast differentiation, secretory IgA immunoglobulin complex, Immunoglobulin lambda variable 6-57, Fibroblast growth factor receptor 3, endochondral bone growth, fibroblast growth factor receptor apoptotic signaling pathway, phototaxis, plasma membrane protein complex, Immunoglobulin lambda variable 2-8, Classical MHC class I antigen, Leukocyte immunoglobulin-like receptor subfamily B member 1, interferon-gamma production, negative regulation of alpha-beta T cell activation, negative regulation of calcium ion transport, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of serotonin secretion, TRA@ protein, Intercellular adhesion molecule 5, salivary gland morphogenesis, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, male gonad development, melanocyte differentiation, positive regulation of JAK-STAT cascade, H-2 class I histocompatibility antigen, K-D alpha chain, positive regulation of intracellular signal transduction, regulation of establishment or maintenance of cell polarity, Interferon alpha/beta receptor 2, JAK-STAT cascade, endochondral ossification, exocyst, receptor tyrosine kinase binding, positive regulation of mitochondrial calcium ion concentration, Methanosarcina mazei, establishment of protein localization to plasma membrane, positive regulation of GTPase activity, regulation of membrane permeability, carbohydrate binding, VEGF-A-activated receptor activity, VEGF-B-activated receptor activity, monocyte chemotaxis, positive regulation of vascular endothelial growth factor receptor signaling pathway, vascular endothelial growth factor receptor-1 signaling pathway, Low affinity immunoglobulin gamma Fc region receptor III-B, Sialic acid-binding Ig-like lectin 5, Cell adhesion molecule-related/down-regulated by oncogenes, interleukin-12 complex, natural killer cell activation, dendritic cell cytokine production, erythrocyte differentiation, humoral immune response, negative regulation of endothelial cell apoptotic process, positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway, Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate., Escherichia coli O157:H7, positive regulation of G-protein coupled receptor protein signaling pathway, Novel immune-type receptor 11, striated muscle myosin thick filament, positive regulation of cytokine secretion, positive regulation of NK T cell differentiation, P-body, peptide hormone binding, Vesicle-associated membrane protein-associated protein B/C, negative regulation by virus of viral protein levels in host cell, sphingolipid biosynthetic process, -!- Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration. -!- The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed., Alpha-amylase SusG, positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process, Immunoglobulin heavy variable 3-23, Interleukin-13 receptor subunit alpha-1, Immunoglobulin kappa variable 1-33, TRAV9-4, Macrophage colony-stimulating factor 1 receptor, osteoclast differentiation, positive regulation of protein serine/threonine kinase activity, Nectin-1, IPT/TIG domain protein, costamere, Histidine kinase., regulation of axon regeneration, negative regulation of lipid storage, Transcription factor COE3, Maltose-binding periplasmic protein, carbohydrate transport, maltose transport complex, transporter activity, Neuroglian, cell adhesion involved in heart morphogenesis, central complex development, epidermal growth factor receptor signaling pathway, imaginal disc morphogenesis, lateral plasma membrane, motor neuron axon guidance, regulation of female receptivity, regulation of tube size, open tracheal system, Basement membrane-specific heparan sulfate proteoglycan core protein, -!- The enzyme from from the bacterium Mycobacterium smegmatis is specific for maltose. -!- It has no activity with alpha-D-glucose. -!- Formerly EC 2.4.1.n5., Anti-colorectal carcinoma light chain, peptidyl-tyrosine phosphorylation, regulation of osteoblast proliferation, interleukin-1, Type I, activating receptor activity, response to interleukin-1, -!- Acts on starch, glycogen and related polysaccharides and oligosaccharides producing beta-maltose by an inversion., innate immune response, positive regulation of T cell cytokine production, positive regulation of ferrous iron binding, fibrinogen complex, integrin binding, positive regulation of gene expression, positive regulation of substrate-dependent cell migration, cell attachment to substrate, substrate adhesion-dependent cell spreading, granulocyte macrophage colony-stimulating factor receptor complex, Serine endopeptidases., cardiac muscle fiber development, muscle filament sliding, Arthrobacter sp. C2-2, Antigen-presenting glycoprotein CD1d, lipid antigen binding, Bacillus halodurans C-125, LRR domain binding, axonal fasciculation, response to activity, PDZ domain binding, beta-catenin binding, bicellular tight junction, MHC class II receptor activity, chemokine metabolic process, IgA binding, cytoskeleton, structural constituent of cytoskeleton, C5a peptidase, cell envelope organization, Igk protein, Transcription factor p65, cellular response to dsRNA, negative regulation of cytokine production, negative regulation of interleukin-12 biosynthetic process, dendrite self-avoidance, peripheral nervous system development, ventral cord development, Exo-beta-D-glucosaminidase, Exo-beta-D-glucosaminidase. Exochitosanase. GlcNase., hydrolase activity, hydrolyzing O-glycosyl compounds, angiogenesis, Cell wall surface anchor family protein, glucose mediated signaling pathway, positive regulation of dendritic cell differentiation, T-cell receptor alpha chain C region, Basal cell adhesion molecule, regulation of store-operated calcium entry, negative regulation of compound eye cone cell fate specification, Glutamate decarboxylase., glutamate decarboxylation to succinate, immune response-regulating cell surface receptor signaling pathway, negative regulation of leukocyte apoptotic process, KDEL motif-containing protein 1, lung epithelium development, spinal cord development, Ig kappa chain V-V region HP 91A3, ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate., Vascular endothelial growth factor receptor 3, negative regulation of interleukin-3 production, Ig kappa chain V-V region HP 123E6, H-2 class II histocompatibility antigen, I-A beta chain, Green fluorescent protein, bioluminescence, Mus musculus, cell surface receptor signaling pathway, ficolin-1-rich granule membrane, neutrophil degranulation, receptor binding, iron ion homeostasis, coreceptor activity, fusion of virus membrane with host plasma membrane, positive regulation of viral entry into host cell, protein kinase binding, receptor activity, Ig gamma-2B chain C region, complement activation, classical pathway, positive regulation of immune response, Bacillus macerans amylase. Cyclodextrin glucanotransferase. Cyclodextrin glycosyltransferase., B cell differentiation, extracellular region, defense response to Gram-negative bacterium, identical protein binding, MHC class I polypeptide-related sequence B, Tissue factor, blood coagulation, extrinsic pathway, integral component of membrane, protein binding, serine-type peptidase complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, integral component of lumenal side of endoplasmic reticulum membrane, interferon-gamma-mediated signaling pathway, transport vesicle membrane, positive regulation of B cell activation, regulation of proteolysis, ciliary neurotrophic factor receptor activity, interleukin-6 receptor complex, positive regulation of osteoblast differentiation, lactose catabolic process, Alpha-galactosidase, Arthrobacter globiformis, Glucodextranase, PAP fimbrial minor pilin protein, growth cone membrane, collagen binding, synaptic membrane, Butyrophilin subfamily 3 member A3, Clostridium perfringens str. 13, Ig lambda-1 chain C region, Sortilin-related receptor, negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process, positive regulation of early endosome to recycling endosome transport, protein retention in Golgi apparatus, protein targeting, negative regulation of viral release from host cell, H-2 class I histocompatibility antigen, TLA(B) alpha chain, transmembrane-ephrin receptor activity, Methanosarcina mazei Go1, anterior/posterior axon guidance, Phosphoglucan phosphatase DSP4, chloroplastic, V165-D-J-C mu protein, Envelope glycoprotein E, positive regulation of synaptic transmission, cholinergic, response to muscle activity, positive regulation of receptor activity, transferrin transport, antigen processing and presentation of exogenous peptide antigen via MHC class Ib, H-2 class I histocompatibility antigen, K-K alpha chain, Putative rhamnosidase, embryonic organ morphogenesis, endodermal digestive tract morphogenesis, fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow, membranous septum morphogenesis, otic vesicle formation, regulation of branching involved in prostate gland morphogenesis, regulation of fibroblast growth factor receptor signaling pathway, Anti-VIPase light chain variable region, Protein B, immunoglobulin production, T cell receptor alpha variable 12-2, Pyrococcus furiosus DSM 3638, Thioester-containing protein I, Carcinoembryonic antigen-related cell adhesion molecule 5, Klebsiella pneumoniae, Hydrocephalus-inducing protein homolog, Cysteine endopeptidases., Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase. Endo-beta-N-acetylglucosaminidase., Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase., Leucine-rich repeats and immunoglobulin-like domains protein 3, HLA class I histocompatibility antigen, B-39 alpha chain, Ig heavy chain V region 3-6, Ig heavy chain V region 5-76, cell fate specification, oviposition, Tail tube protein, Leukocyte immunoglobulin-like receptor subfamily A member 5, Complement C5, Prolactin-inducible protein, blood vessel remodeling, cardiac left ventricle morphogenesis, determination of heart left/right asymmetry, positive regulation of ERBB signaling pathway, Danio rerio, icosahedral viral capsid, Ig kappa chain V-V region L7, Beta-hexosaminidase. Hexosaminidase. N-acetyl-beta-glucosaminidase., Chitobiase, T cell receptor complex, T-cell surface glycoprotein CD3 gamma chain, Collagen alpha-1(XX) chain, Glycosyl hydrolase family 3 N-terminal domain protein, Ephrin type-A receptor 1, Immunoglobulin heavy constant mu, Rhamnogalacturonan exolyase YesX, Cyclizes part of a (1->6)-alpha-D-glucan chain by formation of a (1->6)- alpha-D-glucosidic bond., T cell receptor beta variable 5-1, Scaffolding protein, Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142, Maltogenic amylase, negative thymic T cell selection, -!- Favors pectate, the anion, over pectin, the methyl ester (which is the preferred substrate of EC 4.2.2.10). -!- Formerly EC 4.2.99.3., Putative membrane anchored protein, negative regulation of advanced glycation end-product receptor activity, negative regulation of connective tissue replacement involved in inflammatory response wound healing, regulation of DNA binding, acetylcholine receptor binding, apolipoprotein binding, astrocyte activation involved in immune response, cellular process, cellular response to beta-amyloid, MHC class Ib protein binding, inhibitory MHC class I receptor activity, Down syndrome cell adhesion molecule 1, isoform Y, Bifidobacterium bifidum, H-2 class II histocompatibility antigen, A-U alpha chain, negative regulation of endothelial cell proliferation, generation of precursor metabolites and energy, Pseudomonas putida, chaperone mediated protein folding requiring cofactor, Host cell factor 2, Polymeric immunoglobulin receptor, immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor, compound eye photoreceptor cell differentiation, regulation of smoothened signaling pathway, negative regulation of eosinophil activation, negative regulation of mast cell activation involved in immune response, Cellulose-binding protein, modulation of excitatory postsynaptic potential, nuclear envelope lumen, positive regulation of JUN kinase activity, regulation of synaptic activity, New antigen receptor variable domain, 14L protein, Aspergillus aculeatus, apical part of cell, CfA/I fimbrial subunit A (Colonization factor antigen subunit A putative chaperone), V-set and immunoglobulin domain-containing 4, regulatory region DNA binding, Ig heavy chain V region 102, A band, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, negative regulation of thrombin-activated receptor signaling pathway, HLA class II histocompatibility antigen, DRB1-15 beta chain, AV node cell to bundle of His cell communication, regulation of AV node cell action potential, Interleukin-13 receptor subunit alpha-2, node of Ranvier, Immunoglobulin kappa variable 1-39, T-cell surface glycoprotein CD8 beta chain, Leukemia inhibitory factor receptor, leukemia inhibitory factor receptor activity, cortical actin cytoskeleton, phagocytic cup, HLA class I histocompatibility antigen, alpha chain G, immune response-inhibiting cell surface receptor signaling pathway, positive regulation of tolerance induction, Variable region-beta 8.5, LOC367586 protein, Immunoglobulin heavy variable 4-59, gonad development, Bifidobacterium longum subsp. longum JCM 1217, H-2 class II histocompatibility antigen, A-K alpha chain, ossification involved in bone maturation, semaphorin receptor binding, Ig lambda-1 chain V region, T cell receptor beta, variable 13-1, garland nephrocyte differentiation, nephrocyte filtration, positive regulation of alpha-beta T cell activation, protein antigen binding, Carcinoembryonic antigen-related cell adhesion molecule 8, PapD, interleukin-33 receptor activity, interleukin-33-mediated signaling pathway, ceramide binding, positive regulation of interleukin-4-mediated signaling pathway, TRAV6D-7, glucan 1,4-alpha-glucosidase activity, MHC class I Mamu-A*02, cerebellar granule cell precursor tangential migration, clathrin-coated vesicle, phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, Alpha-1,6-glucan-6-glucanohydrolase., Streptococcus mutans UA159, thrombospondin receptor activity, ventricular cardiac muscle cell action potential, 5'-AMP-activated protein kinase subunit beta-1, -!- Different from EC 3.2.1.142 in its action on glycogen, and its rate of hydrolysis of limit dextrins. -!- Its action on amylopectin is complete. -!- Maltose is the smallest sugar that it can release from an alpha- (1->6)-linkage. -!- Formerly EC 3.2.1.69., Alpha-dextrin endo-1,6-alpha-glucosidase. Amylopectin 6-glucanohydrolase. Debranching enzyme. Limit dextrinase. Pullulan 6-glucanohydrolase., platelet aggregation, positive regulation of substrate adhesion-dependent cell spreading, wound healing, Paracoccus denitrificans, SoxZ protein, hyaluronan catabolic process, negative regulation of platelet-derived growth factor receptor-beta signaling pathway, regulation of transcription from RNA polymerase II promoter, HLA class I histocompatibility antigen, B-27 alpha chain, protein deubiquitination, perinuclear region of cytoplasm, IGL@ protein, Marinomonas primoryensis, DH domain binding, Ephrin type-A receptor 4, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, positive regulation of T cell activation, Fab Hu 15C1 Heavy chain, translation repressor activity, regulation of neuron death, Enterobacteria phage RB49, L-iduronidase activity, interleukin-4 receptor activity, Interleukin-12 subunit beta, negative regulation of interleukin-17 production, positive regulation of interleukin-17 production, positive regulation of natural killer cell activation, positive regulation of osteoclast differentiation, positive regulation of smooth muscle cell apoptotic process, Vk protein, microvillus, negative regulation of angiogenesis, adaptive immune response, antigen processing and presentation of endogenous peptide antigen via MHC class Ib, natural killer cell lectin-like receptor binding, positive regulation of interleukin-13 production, cell-cell junction organization, granulocyte colony-stimulating factor receptor binding, insulin catabolic process, negative regulation by host of viral process, negative regulation of bone resorption, positive regulation of activation-induced cell death of T cells, regulation of endothelial cell migration, Down syndrome cell adhesion molecule 1, isoform BF, T cell receptor alpha variable 11, Interleukin-1 receptor accessory protein-like 1, positive regulation of dendrite morphogenesis, cardiac muscle cell action potential involved in contraction, chemical synaptic transmission, Interleukin-6 receptor subunit alpha, ciliary neurotrophic factor binding, positive regulation of leukocyte chemotaxis, cell part morphogenesis, Nectin-4, Galactose oxidase, Tyrosine-protein phosphatase non-receptor type substrate 1, Saguinus oedipus, Alpha-1,4-glucan:maltose-1-P maltosyltransferase. GMPMT., Neural/ectodermal development factor IMP-L2, interferon-gamma secretion, cell recognition, NK T cell differentiation, late endosome, positive regulation of macrophage activation, Human herpesvirus 4 strain B95-8, neuron cell-cell adhesion, septate junction assembly, Ig gamma-1 chain C region, membrane-bound form, cardiac muscle tissue development, protein localization, Flavobacterium sp. 92, protein N-terminus binding, T-cell surface antigen CD2, intestinal absorption, Beta galactosidase, Listeria innocua Clip11262, Ostrinia furnacalis, Lactobacillus rhamnosus GG, Beta-glucuronidase, type I interferon receptor activity, Ascaris suum, cellular response to thyroid hormone stimulus, melanocyte migration, stem cell factor receptor activity, transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding, apoptotic process, endosome membrane, adhesion of symbiont to host, H-2 class II histocompatibility antigen, A-U beta chain, placental growth factor-activated receptor activity, ureteric bud development, protein phosphorylation, T-cell-specific surface glycoprotein CD28, Myosin-reactive immunoglobulin light chain variable region, Fibroblast growth factor receptor 1, embryonic limb morphogenesis, midbrain development, organ induction, regulation of cell proliferation, Kit signaling pathway, positive regulation of vascular smooth muscle cell differentiation, cell-matrix adhesion, positive regulation of glucose transport, positive regulation of lipid storage, Porphyromonas gingivalis, Nuclear factor NF-kappa-B p105 subunit, Kappa light chain C_region, 5'-AMP-activated protein kinase subunit beta-2, nucleotide-activated protein kinase complex, negative regulation of interleukin-10 production, postsynapse, regulation of T cell mediated cytotoxicity, detection of bacterium, exogenous lipid antigen binding, positive regulation of innate immune response, Malto-oligosyltrehalose trehalohydrolase. Maltooligosyl trehalose trehalohydrolase., Alpha-amylase G-6, Basigin, cadherin binding, monocarboxylic acid transmembrane transporter activity, Programmed cell death 1 ligand 1, peptide antigen-transporting ATPase activity, axon, polysaccharide catabolic process, positive regulation of phosphatidylinositol 3-kinase signaling, G-protein coupled receptor binding, cell leading edge, integrin complex, -!- The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168 and Aspergillus aculeatus., Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D- galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non- reducing end., -!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor., Two-component system sensor histidine kinase/response, activation of transmembrane receptor protein tyrosine kinase activity, ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing, cell chemotaxis, maltose transport, interleukin-2 receptor activity, positive regulation of multicellular organism growth, FFAT motif binding, microtubule binding, NIK/NF-kappaB signaling, T-helper 1 type immune response, starch catabolic process, negative regulation of interleukin-12 secretion, 1,4-alpha-glucan branching enzyme., glycogen biosynthetic process, Gram-negative pili assembly chaperone, N-terminal domain protein, T-cell receptor beta chain V region C5, Methanosarcina acetivorans C2A, bone development, bone mineralization, embryonic organ development, epithelial cell proliferation, epithelial cell proliferation involved in salivary gland morphogenesis, lung lobe morphogenesis, mesenchymal cell differentiation involved in lung development, regulation of multicellular organism growth, reproductive structure development, cell adhesion molecule binding, cell-cell junction, positive regulation of phospholipase activity, immune response, platelet-derived growth factor receptor binding, 4-alpha-D-glucan maltohydrolase. Glycogenase. Saccharogen amylase., HLA class I histocompatibility antigen, A-2 alpha chain, Protein FimH, host cell membrane, 1,4-beta-poly-N-acetylglucosaminidase. Chitodextrinase. Poly-beta-glucosaminidase., Interferon gamma receptor 1, response to virus, extracellular matrix organization, peptide cross-linking, platelet alpha granule lumen, platelet degranulation, regulation of ERK1 and ERK2 cascade, -!- Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108)., Beta-galactosidase, alkali metal ion binding, beta-galactosidase activity, positive regulation of calcium-mediated signaling, cellular response to tumor necrosis factor, cytokine secretion involved in immune response, VPS10 domain-containing receptor SorCS2, Myosin-binding protein C, fast-type, cardiac myofibril assembly, Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104, receptor-mediated endocytosis, cellular response to DNA damage stimulus, NF-kappaB complex, actinin binding, animal organ morphogenesis, negative regulation of protein catabolic process, regulation of inflammatory response, sequence-specific DNA binding, Interleukin-6 receptor subunit beta, ciliary neurotrophic factor-mediated signaling pathway, IGK@ protein, axon guidance, cytoskeletal protein binding, learning or memory, response to amphetamine, HLA class I histocompatibility antigen, B-18 alpha chain, HLA class I histocompatibility antigen, B-53 alpha chain, Debranching enzyme., Isoamylase., Pseudomonas amyloderamosa, CNTFR-CLCF1 complex, (1) [Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine + H(2)O = [protein]-L-serine + N-acetyl-D-glucosamine. (2) [Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonine + H(2)O = [protein]-L-threonine + N-acetyl-D-glucosamine., Ani2.3 TCR A chain, glycogen catabolic process, negative regulation of T-helper 1 type immune response, negative regulation of defense response to bacterium, positive regulation of interleukin-1 production, toll-like receptor 3 signaling pathway, cell fate determination, long-term memory, positive regulation of G1/S transition of mitotic cell cycle, -!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate., metanephric distal tubule morphogenesis, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle, bleb assembly, positive regulation of wound healing, Selection and upkeep of intraepithelial T-cells protein 1, cell periphery, positive regulation of protein kinase C signaling, enamel mineralization, positive regulation of interleukin-8 secretion, antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, clathrin-coated vesicle membrane, positive regulation of ERK1 and ERK2 cascade, positive regulation of transcription, DNA-templated, immunoglobulin mediated immune response, phagocytosis, engulfment, Ig kappa chain C region, -!- Strongly activated by glycine and stabilized by calcium. -!- Belongs to peptidase family C25., Porphyromonas gingivalis W83, antibacterial humoral response, early endosome lumen, positive regulation of transferrin receptor binding, regulation of membrane depolarization, retina homeostasis, tertiary granule lumen, Bacillus sp. 1011, E3 ubiquitin-protein ligase TRIM9, Leptospira interrogans serovar Lai str. 56601, Homo sapiens, plasma membrane, MHC class II protein complex binding, T cell receptor signaling pathway, lysosomal membrane, trans-Golgi network membrane, Receptor-type tyrosine-protein phosphatase eta, negative regulation of myotube differentiation, peptidase activity, Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -(Man(GlcNAc)(2))Asn- structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact., Columba livia, V(H) region of G5 Bb 2.2, Ovis aries, lymphocyte activation, T-cell immunoglobulin and mucin domain-containing protein 2, Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends., regulation of exocyst assembly, negative regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-2 secretion, Calmodulin-binding transcription activator 1, Saccharomyces cerevisiae S288C, leading edge membrane, regulation of cell adhesion mediated by integrin, blood vessel endothelial cell fate specification, blood vessel lumenization, cell fate commitment, positive regulation of Notch signaling pathway involved in heart induction, Ig heavy chain V region MC101, inhibitory synapse, Protein-glutamine gamma-glutamyltransferase K, intrinsic component of membrane, positive regulation of keratinocyte proliferation, cellulose catabolic process, negative regulation of beta-amyloid formation, recycling endosome, regulation of smooth muscle cell migration, protein localization to microtubule, T cell mediated cytotoxicity, response to heat, Ephrin type-B receptor 1, antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent, Xyloglucan + H(2)O = xyloglucan oligosaccharides., Xyloglucan-specific endo-beta-1,4-glucanase BoGH5A, xyloglucan catabolic process, Bacillolysin, Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130, Cell adhesion molecule 2, amylopectin binding, Muscle, skeletal receptor tyrosine protein kinase, IFN-alpha/beta binding protein C12R, Low affinity immunoglobulin gamma Fc region receptor II-c, positive regulation of CD40 signaling pathway, cellular iron ion homeostasis, cytoplasmic vesicle, iron ion import across plasma membrane, positive regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of antigen processing and presentation, positive regulation of natural killer cell differentiation, Ig heavy chain V region 36-60, Trem-like transcript 1 protein, Receptor-type tyrosine-protein phosphatase mu, cell migration involved in sprouting angiogenesis, negative regulation of cell migration, Yaba-like disease virus, retinal cell programmed cell death, HLA class I histocompatibility antigen, B-40 alpha chain, regulation of cytokine production, sarcomere, Immunoglobulin lambda constant 1, establishment of skin barrier, negative regulation of Rho protein signal transduction, Immunoglobulin kappa chain variable 4-54, platelet-derived growth factor receptor-beta signaling pathway, frizzled binding, heparan sulfate binding, modulation of age-related behavioral decline, negative regulation of calcium ion import across plasma membrane, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein metabolic process, Interleukin-1 receptor type 2, chondroitin sulfate proteoglycan binding, neuron projection regeneration, HLA class I histocompatibility antigen, A-68 alpha chain, Serine-rich adhesin for platelets, glycolipid binding, lipopeptide binding, Contactin-6, Ig gamma-2A chain C region secreted form, chordate embryonic development, positive regulation of endothelial cell chemotaxis to fibroblast growth factor, Myelin-oligodendrocyte glycoprotein, regulation of T cell receptor signaling pathway, Glycogen debranching enzyme, AV node cell-bundle of His cell adhesion involved in cell communication, germ cell migration, regulation of defense response to virus by host, positive regulation of locomotion, Mycobacterium thermoresistibile ATCC 19527, -!- Adds an N(7)-methylguanine cap to mRNA. -!- The nucleoside next to the terminal guanosine may be either guanosine or adenosine., GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA., regulation of natural killer cell mediated cytotoxicity, -!- Acts on N-acetylglucosides and N-acetylgalactosides. -!- Formerly EC 3.2.1.29 and EC 3.2.1.30., T-cell surface glycoprotein CD3 epsilon chain, signal complex assembly, voltage-gated sodium channel activity involved in cardiac muscle cell action potential, regulation of axon extension involved in axon guidance, Immunoglobulin heavy constant gamma 4, positive regulation of immunoglobulin mediated immune response, regulation of viral entry into host cell, CD1D antigen, d polypeptide, establishment of mitochondrion localization, Protease, cytoskeleton organization, Beta-glucosidase, co-receptor binding, Filamin-B, negative regulation of toll-like receptor 9 signaling pathway, 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase, Beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine + phosphate = alpha-D-galactopyranose 1-phosphate + N-acetyl-D-glucosamine., Immunglobulin heavy chain variable region, Escherichia coli O127:H6 str. E2348/69, Semaphorin-4D, protein heterooligomerization, Trypsin, putative, Ig heavy chain V-III region J606, Nuclear factor NF-kappa-B p100 subunit, Poliovirus receptor, susceptibility to natural killer cell mediated cytotoxicity, regulation of interleukin-12 production, 4-alpha-D-glucan glucohydrolase. Amyloglucosidase. Exo-1,4-alpha-glucosidase. Gamma-amylase. Glucoamylase. Lysosomal alpha-glucosidase., Aspergillus niger, membrane raft polarization, Class II histocompatibility antigen, M alpha chain, Junctional adhesion molecule-like, gamma-delta T cell activation, inositol-1,4,5-trisphosphate 5-phosphatase activity, Endohydrolysis of (1->6)-alpha-D-glucosidic linkages in dextran., uncultured bacterium, cerebellar mossy fiber, positive regulation of synapse assembly, cell-cell junction maintenance, mammary gland duct morphogenesis, Ig heavy chain V region 914, macroautophagy, negative regulation of cytotoxic T cell degranulation, mitotic spindle assembly, nucleolus, brain morphogenesis, entrainment of circadian clock, outflow tract morphogenesis, regulation of epithelial cell migration, open tracheal system, negative regulation of B cell proliferation, Killer cell immunoglobulin-like receptor 2DL3, Hemolin, stress-activated MAPK cascade, type I interferon biosynthetic process, negative regulation of antigen processing and presentation of peptide antigen via MHC class II, Trichoderma reesei, transcription cofactor activity, transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding, leukocyte cell-cell adhesion, High affinity nerve growth factor receptor, positive regulation of Ras protein signal transduction, positive regulation of interleukin-4 production, regulatory T cell differentiation, middle ear morphogenesis, paraxial mesoderm development, positive regulation of mitotic cell cycle DNA replication, vasculogenesis involved in coronary vascular morphogenesis, ventricular zone neuroblast division, hemopoiesis, mast cell degranulation, positive regulation of sequence-specific DNA binding transcription factor activity, Angiopoietin-1 receptor, protein kinase activity, protein oligomerization, dendrite morphogenesis, neuron projection morphogenesis, brain development, chondrocyte differentiation, Cyclomaltodextrin + H(2)O = linear maltodextrin., hemoglobin complex, endocrine pancreas development, Bacillus licheniformis DSM 13 = ATCC 14580, histone H4-K16 acetylation, dendritic shaft, protein complex binding, Adnectin, Mycobacterium tuberculosis H37Rv, cell proliferation, Paenibacillus macerans, positive regulation of NK T cell proliferation, positive regulation of T-helper 1 type immune response, positive regulation of cell adhesion, regulation of type I interferon-mediated signaling pathway, type I interferon binding, Hepatitis A virus cellular receptor 1 homolog, phosphatidylserine binding, Beta-galactose oxidase., 3M complex, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, common myeloid progenitor cell proliferation, negative regulation of granulocyte differentiation, negative regulation of protein kinase activity, positive regulation of JNK cascade, positive regulation of vasculogenesis, virion binding, Immunoglobulin heavy constant alpha 1, glomerular filtration, positive regulation of extrinsic apoptotic signaling pathway, chondrocyte proliferation, skeletal system development, HLA class I histocompatibility antigen, B-42 alpha chain, gamete generation, positive regulation of oocyte development, JAK-STAT cascade involved in growth hormone signaling pathway, insulin-like growth factor receptor signaling pathway, response to estradiol, beta-tubulin binding, negative regulation by host of viral release from host cell, hemidesmosome assembly, skin development, positive regulation of protein targeting to mitochondrion, Alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase. RG-lyase. Rgase B. Rhamnogalacturonase B., Lmo1290 protein, negative regulation of mononuclear cell proliferation, negative regulation of osteoclast development, signaling receptor activity, MHC class I molecule, cytokine secretion, Human gammaherpesvirus 4, Interleukin-2 receptor subunit beta, H-2 class II histocompatibility antigen, E-K alpha chain, detection of tumor cell, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 biosynthetic process, Secreted protein BARF1, cell junction assembly, -!- Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages., Cell surface protein SpaA, T cell receptor alpha variable 20, Escherichia coli P0301867.5, Caenorhabditis elegans, complement component C1q binding, synapse, Bacteroides ovatus ATCC 8483, Isoamylase, ectopic germ cell programmed cell death, erythropoietin-mediated signaling pathway, hematopoietic stem cell migration, myeloid progenitor cell differentiation, regulation of developmental pigmentation, activating transcription factor binding, cellular response to interleukin-1, negative regulation of NIK/NF-kappaB signaling, positive regulation of miRNA metabolic process, positive regulation of type I interferon production, regulation of NIK/NF-kappaB signaling, repressing transcription factor binding, transcription factor complex, mitotic chromosome condensation, muscle alpha-actinin binding, positive regulation of protein secretion, protein self-association, regulation of catalytic activity, structural constituent of muscle, Ig heavy chain V region T601, cell migration, RNA polymerase II regulatory region sequence-specific DNA binding, ankyrin repeat binding, hair follicle development, response to muscle stretch, granulocyte colony-stimulating factor binding, cytokine-mediated signaling pathway, interleukin-27-mediated signaling pathway, negative regulation of interleukin-6-mediated signaling pathway, Yersinia pestis, laminin binding, negative regulation of mast cell activation, G-protein coupled receptor signaling pathway, complement activation, alternative pathway, positive regulation of activated T cell proliferation, Ig kappa chain V region Mem5, IgG-2a protein, Man26A, 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase., Hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-((1->4)- alpha-D-glucanosyl)(n) trehalose to yield trehalose and (1->4)-alpha-D- glucan., pathogenesis, negative regulation of activated T cell proliferation, negative regulation of interferon-gamma production, positive regulation of interleukin-10 secretion, Enterochelin esterase, cellular response to cytokine stimulus, cellular response to macrophage colony-stimulating factor stimulus, macrophage colony-stimulating factor receptor activity, ruffle organization, positive regulation of transcription from RNA polymerase II promoter, Exo-1,4-beta-D-glucosaminidase., positive regulation of macroautophagy, positive regulation of positive chemotaxis, vascular endothelial growth factor binding, vascular endothelial growth factor receptor signaling pathway, autophagy, digestive tract development, Alpha-amylase., Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units., Bacillus cereus ATCC 14579, Interleukin-10 receptor subunit beta, Transcription factor COE1, maltose binding, TAP1 binding, IgG receptor activity, interleukin-15-mediated signaling pathway, membrane raft, transmembrane signaling receptor activity, Ig kappa chain V-II region 26-10, positive regulation of type IIa hypersensitivity, HFE-transferrin receptor complex, antimicrobial humoral immune response mediated by antimicrobial peptide, cytosol, defense response to Gram-positive bacterium, early endosome membrane, regulation of immune response, erythropoietin receptor activity, negative regulation of defense response to virus by host, response to oxidative stress, EVM013, phospholipid binding, branching involved in prostate gland morphogenesis, lens fiber cell development, mammary gland bud formation, regulation of cell fate commitment, Actinomyces naeslundii, glycogen debranching enzyme activity, Glycoside hydrolase family 9, positive regulation of vascular endothelial growth factor production, fibroblast growth factor receptor binding, Ighg protein, 1-phosphatidylinositol-3-kinase activity, Fibroblast growth factor receptor 2, nucleus, signal transducer activity, positive regulation of CD8-positive, alpha-beta T cell activation, protein binding involved in protein folding, -!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine crosslinks., Immunoglobulin lambda constant 2, Ig heavy chain V region M603, H-2 class I histocompatibility antigen, K-B alpha chain, Chitinase A, interferon-gamma receptor activity, disordered domain specific binding, negative regulation of transforming growth factor-beta secretion, proteinaceous extracellular matrix, RIMS-binding protein 2, neutrophil mediated killing of gram-negative bacterium, neutrophil activation, neutrophil mediated immunity, muscle contraction, Streptococcus pyogenes, -!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70., Z disc, calmodulin binding, protein maturation, RING E3 ligase. Ubiquitin transferase RING E3., negative regulation of viral entry into host cell, negative regulation of viral transcription, phosphatidylinositol 3-kinase binding, Branchiostoma floridae, positive regulation of cytosolic calcium ion concentration, response to electrical stimulus, positive regulation of protein localization to plasma membrane, BMP signaling pathway, basal part of cell, Glycoprotein E, CARDB domain lipoprotein, putative, Motile sperm domain-containing protein 2, protein deglycosylation, negative regulation of macrophage activation, Endoglucanase D, Streptococcus pyogenes MGAS10394, Trypsin-resistant surface T6 protein, spinal cord ventral commissure morphogenesis, carbohydrate phosphatase activity, Defective proboscis extension response 6, isoform C, Chitinase A1, Suppressor of hairless protein, crystal cell differentiation, Striated muscle preferentially expressed protein kinase, mesonephric duct development, metanephric proximal tubule development, regulation of proteasomal protein catabolic process, H-2 class I histocompatibility antigen, L-D alpha chain, NT-3 growth factor receptor, [Myosin light-chain] kinase., stress fiber, Hepatitis A virus cellular receptor 2, basement membrane organization, myelination in peripheral nervous system, desmosome organization, natural killer cell tolerance induction, negative regulation of myeloid dendritic cell activation, macrophage activation involved in immune response, positive regulation of defense response to bacterium, Archaeoglobus fulgidus DSM 4304, magnesium ion binding, cellular response to interferon-gamma, Beta-2-microglobulin, ferric iron import, positive regulation of T cell mediated cytotoxicity, MHC class II protein binding, enzyme linked receptor protein signaling pathway, positive regulation of T cell anergy, negative regulation of macrophage chemotaxis, Leptin receptor, energy reserve metabolic process, labyrinthine layer blood vessel development, negative regulation of ossification, regulation of timing of cell differentiation, somatic stem cell population maintenance, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding, Contactin-3, TRADV16D, negative regulation of protein phosphorylation, T-cell surface glycoprotein CD3 delta chain, mast cell activation, Tripartite motif-containing protein 45, Glycerophosphocholine phosphodiesterase GPCPD1, Glycerophosphocholine phosphodiesterase., GTP--RNA guanylyltransferase. mRNA capping enzyme., Beta-N-acetylhexosaminidase., Single chain Fv, Pectobacterium carotovorum, HDV103S1, Sialic acid-binding Ig-like lectin 8, Leukocyte immunoglobulin-like receptor subfamily A member 2, Endo-pectate lyase, Pectate lyase., induction of positive chemotaxis, HLA class I histocompatibility antigen, Cw-8 alpha chain, Brother of CDO, positive regulation of myoblast differentiation, Klebsiella aerogenes, Fimbrial adapter PapK, SLAM family member 6, Carcinoembryonic antigen family member protein, Putative surface-anchored fimbrial subunit, Oligo alginate lyase, Hepatitis B virus receptor binding protein, immunoglobulin binding, positive regulation of calcium ion transport into cytosol, negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process, Shigella flexneri 2850-71, heart morphogenesis, myosin heavy chain binding, Immunoglobulin lambda-like polypeptide 1, entry of bacterium into host cell, negative regulation of stress fiber assembly, positive chemotaxis, positive regulation of endothelial cell chemotaxis, positive regulation of microtubule polymerization, FLJ00385 protein, ficolin-1-rich granule lumen, Platelet-derived growth factor receptor beta, antifungal humoral response, positive regulation of excitatory postsynaptic potential, positive regulation of long-term synaptic potentiation, protein homooligomerization, serine-type endopeptidase inhibitor activity, negative regulation of inflammatory response to antigenic stimulus, cytokine receptor activity, Glucanase, B cell proliferation, T-cell receptor gamma-2 chain C region, T-cell surface glycoprotein CD1b, negative regulation of NK T cell activation, negative regulation of phagocytosis, engulfment, Irregular chiasm C-roughest protein, delta-catenin binding, GPI anchor binding, Uro-adherence factor A, positive regulation of sarcomere organization, nuclear export, Staphylococcus aureus subsp. aureus NCTC 8325, Netrin receptor UNC5D, Nectin-3, retina morphogenesis in camera-type eye, Aspergillus oryzae, regulation of cell differentiation, Vascular cell adhesion protein 1, alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex, Notch signaling pathway, dauer exit, [Clostridium] cellulolyticum, apical junction complex, positive regulation of cell-cell adhesion, Metalloendopeptidases., Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa., Amygdalase. Beta-D-glucoside glucohydrolase. Cellobiase. Gentobiase., Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose., Hemagglutinin glycoprotein, Glycoprotein UL18, SAM domain binding, Slit-Robo signaling complex, axonal growth cone, heparin binding, locomotion involved in locomotory behavior, phosphoprotein phosphatase activity, Beta-glucuronidase., beta-glucuronidase activity, positive regulation of epithelial cell proliferation involved in wound healing, pharyngeal system development, Golgi-associated vesicle, inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity, phosphatidylinositol phosphate 4-phosphatase activity, regulation of GTPase activity, Leucine-rich repeat-containing protein 4B, Anti-myosin immunoglobulin heavy chain variable region, regulation of macroautophagy, Filamin-A, negative regulation of sequence-specific DNA binding transcription factor activity, protein localization to cell surface, calcium-independent cell-matrix adhesion, T cell receptor beta variable 6-5, Carcinoembryonic antigen-related cell adhesion molecule 7, negative regulation of calcidiol 1-monooxygenase activity, cuticle pattern formation, Beta/alpha-amylase, Mc5 VHCH1, negative regulation of mammary gland epithelial cell proliferation, Immunoglobulin iota chain, response to lipopolysaccharide, 1,4-alpha-glucan-branching enzyme, Ac-ChiA, HLA class I histocompatibility antigen, B-58 alpha chain, positive regulation of interferon-gamma secretion, -!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15., Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates., positive regulation of cytokine-mediated signaling pathway, macrophage differentiation, Attaching and effacing protein, pathogenesis factor EaeH, T-cell receptor, sp3.4 alpha chain, Sodium channel subunit beta-3, regulation of ventricular cardiac muscle cell membrane depolarization, positive regulation of interleukin-6 secretion, neurotrophin binding, microtubule-based movement, neurotrophin TRK receptor signaling pathway, SH3/SH2 adaptor activity, Vesicle-associated membrane protein-associated protein A, nuclear membrane, T cell receptor beta variable 9, acute-phase response, positive regulation of smooth muscle cell proliferation, transcription coactivator activity, CTLA-4 protein, dendritic spine, branching morphogenesis of a nerve, Protein lin-41, nematode male tail tip morphogenesis, Chaperone protein FaeE, glucan biosynthetic process, growth, interleukin-5 receptor activity, HLA class I histocompatibility antigen, A-3 alpha chain, Alpha-L-iduronidase, glycosaminoglycan catabolic process, regulation of leukocyte mediated cytotoxicity, positive regulation of NF-kappaB import into nucleus, positive regulation of mononuclear cell proliferation, retinal ganglion cell axon guidance, synaptic growth at neuromuscular junction, Gelation factor, transmembrane transport, protein tyrosine phosphatase activity, brush border membrane, negative regulation of JNK cascade, protein tyrosine kinase binding, viral entry into host cell, positive regulation of respiratory burst, Thermus thermophilus HB8, regulation of development, heterochronic, Down syndrome cell adhesion molecule 1, isoform AG, Osteoclast-associated immunoglobulin-like receptor, T-cell immunoglobulin and mucin domain-containing protein 4, Sodium channel subunit beta-2, regulation of heart rate by cardiac conduction, sodium channel regulator activity, Bcl3/NF-kappaB2 complex, Alpha-maltose 1-phosphate + ((1->4)-alpha-D-glucosyl)(n) = phosphate + ((1->4)-alpha-D-glucosyl)(n+2)., Mycobacterium tuberculosis CDC1551, Starch synthase (maltosyl-transferring)., adherens junction organization, receptor clustering, Chlamydomonas reinhardtii, HLA-A specific inhibitory MHC class I receptor activity, HLA-B specific inhibitory MHC class I receptor activity, negative regulation of dendritic cell apoptotic process, negative regulation of interferon-beta secretion, positive regulation of gamma-delta T cell activation involved in immune response, Neogenin, negative regulation of axon regeneration, positive regulation of BMP signaling pathway, immunoglobulin production involved in immunoglobulin mediated immune response, male courtship behavior, photoreceptor cell axon guidance, basement membrane, embryonic skeletal system morphogenesis, glycosaminoglycan biosynthetic process, positive regulation of exocytosis, single organismal cell-cell adhesion, positive regulation of myeloid cell differentiation, Lin1840 protein, Alicyclobacillus acidocaldarius subsp. acidocaldarius, Lambda-chain (AA -20 to 215), Synaptogenesis protein syg-2, synaptic target recognition, sensory perception of sound, mast cell cytokine production, mast cell proliferation, definitive hemopoiesis, response to interferon-alpha, response to radiation, chromatin DNA binding, transcription factor activity, RNA polymerase II core promoter sequence-specific, MDA-5 signaling pathway, positive regulation of interferon-beta production, transcription from RNA polymerase II promoter, H-2 class II histocompatibility antigen, A-B alpha chain, establishment of endothelial intestinal barrier, scaffold protein binding, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phospholipase C activity, HLA class I histocompatibility antigen, B-44 alpha chain, response to calcium ion, sarcomere organization, Neural cell adhesion molecule 1, Rattus norvegicus, growth cone, negative regulation of cell death, neuron development, peripheral nervous system axon regeneration, response to inorganic substance, protein complex, transepithelial transport, cellular response to interferon-alpha, catalytic activity, If kappa light chain, defense response to bacterium, inner ear development, T-cell surface glycoprotein CD1a, response to drug, positive regulation of interleukin-12 biosynthetic process, early endosome to late endosome transport, leukemia inhibitory factor signaling pathway, positive regulation of T cell proliferation, ENSMUSG00000076577 protein, Hydrolysis of chitosan or chitosan oligosaccharides to remove successive D-glucosamine residues from the non-reducing termini., Advanced glycosylation end product-specific receptor, S100 protein binding, inflammatory response, negative regulation of granulocyte macrophage colony-stimulating factor production, TAP2 binding, positive regulation of mitochondrial depolarization, positive regulation of nitric-oxide synthase biosynthetic process, signal transducer, downstream of receptor, with protein tyrosine kinase activity, Protein-tyrosine-phosphatase., amelogenesis, Myosin-binding protein C, slow-type, azurophil granule lumen, detection of mechanical stimulus involved in sensory perception of touch, Amycolatopsis orientalis, determination of adult lifespan, Prolactin receptor, prolactin receptor activity, ATP-binding cassette (ABC) transporter complex, detection of maltose stimulus, detection of stimulus, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, Leukocyte-associated immunoglobulin-like receptor 1, Major histocompatibility complex class I, Antigen-presenting glycoprotein CD1d1, positive regulation of interferon-gamma biosynthetic process, growth hormone receptor complex, Cobra venom factor, T-helper 1 cell differentiation, T-cell surface glycoprotein CD1A1 antigen, alpha-amylase activity, Collagen adhesion protein, Protein FimG, Interleukin-22 receptor subunit alpha-1, regulation of actin cytoskeleton reorganization, positive regulation of calcium ion transport, positive regulation of C-C chemokine receptor CCR7 signaling pathway, positive regulation of antigen processing and presentation of peptide antigen via MHC class II, negative regulation of T cell cytokine production, response to iron ion, Kin of IRRE-like protein 3, T-cell surface glycoprotein CD8 alpha chain, cytotoxic T cell differentiation, secretory granule membrane, iron ion transport, protein refolding, response to molecule of bacterial origin, T cell differentiation, T cell selection, interleukin-16 binding, positive regulation of MAPK cascade, regulation of calcium ion transport, signal transduction, Kappa light chain, Cyclizes part of a (1->4)-alpha-D-glucan chain by formation of a (1->4)- alpha-D-glucosidic bond., Fimbrial structural subunit, amylo-alpha-1,6-glucosidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, protease binding, Tyrosine-protein kinase Mer, Exo-(1->4)-beta-D-galactanase. Lactase., Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides., Beta-amylase., High affinity immunoglobulin epsilon receptor subunit alpha, MHC class I protein complex, positive regulation of CD8-positive, alpha-beta T cell proliferation, Chaperone protein FimC, HLA class II histocompatibility antigen, DRB1-1 beta chain, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, cellular response to lipopolysaccharide, recycling endosome membrane, Immunoglobulin heavy constant gamma 1, Erythropoietin receptor, -!- The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act. -!- Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase. -!- Cf. EC 3.2.1.202., Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta- linkages in chitin and chitodextrins., H-2 class I histocompatibility antigen, D-B alpha chain, Fibronectin, chaperone binding, interaction with symbiont, Golgi membrane, MHC class II protein complex, C5a peptidase., cardiac muscle tissue morphogenesis, protein serine/threonine kinase activity, regulation of protein kinase activity, Ruminiclostridium thermocellum, ADP-ribosylation factor binding, low-density lipoprotein particle binding, positive regulation of protein exit from endoplasmic reticulum, positive regulation of protein localization to early endosome, RING-type E3 ubiquitin transferase., positive regulation of autophagy, positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, Tyrosine-protein kinase receptor TYRO3, Yersinia enterocolitica, positive regulation of fibroblast growth factor receptor signaling pathway, presynaptic membrane, Immunoblobulin light chain, Pectate lyase, neuron projection membrane, CD1-2 antigen, Similar, but not identical, to that of thermolysin., Butyrophilin subfamily 3 member A2, VDJ complex, Histocompatibility 2, M region locus 3, positive regulation of nitric oxide biosynthetic process, Ciliary neurotrophic factor receptor subunit alpha, -!- Within higher eukaryotes post-translational modification of protein serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic, inducible and abundant, regulating many cellular processes by interfering with protein phosphorylation. -!- EC 2.4.1.155 transfers GlcNAc onto substrate proteins and EC 3.2.1.169 cleaves GlcNAc from the modified proteins., Protein O-GlcNAcase., beta-N-acetylglucosaminidase activity, OX-2 membrane glycoprotein, Fc receptor-like A, Streptococcus pneumoniae, H-2 class I histocompatibility antigen, Q7 alpha chain, Sperm-specific class P protein 34, Cortical-lytic enzyme, embryonic pattern specification, negative regulation of mitotic nuclear division, organ growth, positive regulation of epithelial cell proliferation involved in lung morphogenesis, pyramidal neuron development, camera-type eye morphogenesis, negative regulation of granulocyte colony-stimulating factor production, negative regulation of tumor necrosis factor production, positive regulation of tumor necrosis factor secretion, toll-like receptor 7 signaling pathway, toll-like receptor 9 signaling pathway, Putative outer membrane or exported protein, asymmetric cell division, H-2 class II histocompatibility antigen, A-D beta chain, Myelin protein P0, -!- Requires calmodulin for activity. -!- The 20 kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, more slowly. -!- Formerly EC 2.7.1.117., protein localization to cell junction, Mammalian orthoreovirus 3 Dearing, Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides., establishment or maintenance of cell polarity, mitogen-activated protein kinase binding, negative regulation of cell growth, Escherichia virus Lambda, Amphoterin-induced protein 1, regulation of apoptotic process, Staphylothermus marinus F1, V2-17 protein, positive regulation of cell proliferation involved in heart morphogenesis, sebaceous gland development, Cyclodextrin glucanotransferase, Meleagris gallopavo, Telokin, Ectromelia virus, anchored component of plasma membrane, chemokine activity, membrane attack complex, aspartic-type endopeptidase activity, intrinsic apoptotic signaling pathway in response to DNA damage, protein kinase B signaling, Interleukin-22 receptor subunit alpha-2, VP1, Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S, auditory receptor cell fate commitment, endocardium morphogenesis, MAML1-RBP-Jkappa- ICN1 complex, Beta-xylanase, excretion, Ig kappa chain V-V region HP 93G7, protein autoprocessing, response to hypoxia, ubiquitin binding, HLA class I histocompatibility antigen, B-81 alpha chain, Acting on polysaccharides., Paired immunoglobulin-like type 2 receptor alpha, Cytochrome c, Thermus sp. IM6501, epithelial cell morphogenesis, Aberrantly recombined kappa chain Vk8/J1 region, spleen development, Carbohydrate binding family 6, Neopullulanase (Alpha-amylase II), V-set and immunoglobulin domain-containing protein 4, Rho GTPase binding, actin crosslink formation, ion channel binding, positive regulation of potassium ion transmembrane transport, positive regulation of transcription factor import into nucleus, potassium channel regulator activity, cellular response to mechanical stimulus, response to osmotic stress, ventricular cardiac muscle tissue morphogenesis, Leucine-rich repeat-containing protein 4, negative regulation of NF-kappaB transcription factor activity, negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway, Hepatocyte growth factor receptor, AV node cell action potential, Hypothetical fimbrial-like protein ydeQ, chemorepulsion involved in postnatal olfactory bulb interneuron migration, positive regulation of Rho protein signal transduction, Sus scrofa, glycogen metabolic process, positive regulation of germinal center formation, Ig kappa chain V-III region PC 7043, Alpha-neuraminidase. N-acylneuraminate glycohydrolase. Neuraminidase. Sialidase., Micromonospora viridifaciens, Tyrosine-protein kinase receptor UFO, Protein sidekick-2, positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway, positive regulation of phosphoprotein phosphatase activity, positive regulation of smooth muscle cell migration, PTB domain binding, acetylcholine receptor activator activity, positive regulation of cellular response to tunicamycin, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, MHC Rfp-Y class I alpha chain, I-kappaB/NF-kappaB complex, positive regulation of T cell differentiation in thymus, T cell activation involved in immune response, LOC100046793 protein, negative regulation of B cell receptor signaling pathway, negative regulation of activation of JAK2 kinase activity, negative regulation of cardiac muscle cell proliferation, Ruminiclostridium thermocellum ATCC 27405, Type I pullulanase, coreceptor-mediated virion attachment to host cell, acrosome assembly, spermatid nucleus differentiation, zonula adherens, actin filament organization, hematopoietic progenitor cell differentiation, -!- Wide specificity for beta-D-glucosides. -!- Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides., Kluyveromyces marxianus, Zinc-alpha-2-glycoprotein, T cell receptor alpha variable 21, cytoskeletal anchoring at plasma membrane, D-galactose + O(2) = D-galacto-hexodialdose + H(2)O(2)., Fusarium graminearum, epithelial cell migration, open tracheal system, regulation of dendrite development, Ctenopharyngodon idella, leukocyte aggregation, positive regulation of collateral sprouting, -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4., Trypsin., Vibrio cholerae O1 biovar El Tor str. N16961, compound eye morphogenesis, nephrocyte diaphragm, nephrocyte diaphragm assembly, regulation of striated muscle tissue development, T cell receptor beta variable 12-4, host cell surface, smoothened signaling pathway, atrial cardiac muscle cell action potential, Moritella marina, HLA class II histocompatibility antigen, DP alpha 1 chain, heparan sulfate proteoglycan binding, interleukin-4 secretion, positive regulation of interleukin-5 production, regulation of T cell anergy, interleukin-13-mediated signaling pathway, Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose., polysaccharide metabolic process, startle response, Galacto-N-biose phosphorylase. Lacto-N-biose phosphorylase. LNBP., Ig heavy chain V region 5-84, limb bud formation, Inositol polyphosphate 5-phosphatase OCRL-1, inositol phosphate metabolic process, inositol phosphate phosphatase activity, Leukocyte surface antigen CD47, Neuronal cell adhesion molecule, Antigen, B-cell receptor, Mast/stem cell growth factor receptor Kit, activation of MAPK activity, basal plasma membrane, response to interferon-beta, cartilage development involved in endochondral bone morphogenesis, Cyclomaltodextrinase, Cyclomaltodextrinase., Ral GTPase binding, T cell activation, B cell affinity maturation, positive regulation of Rho guanyl-nucleotide exchange factor activity, MpAFP_RII tetra-tandemer, neuron differentiation, presynaptic membrane assembly, Interleukin-5 receptor subunit alpha, L-iduronidase., MLL1 complex, histone H4-K5 acetylation, cell cycle arrest, interferon-gamma biosynthetic process, positive regulation of activation of Janus kinase activity, positive regulation of lymphocyte proliferation, positive regulation of tumor necrosis factor production, cell differentiation, Obscurin-like protein 1, regulation of mitotic nuclear division, T-lymphocyte activation antigen CD80, Neopullulanase, Peyer's patch development, ciliary membrane, granulocyte colony-stimulating factor signaling pathway, negative regulation of vascular permeability, positive regulation of CD4-positive, alpha-beta T cell activation, regulation of sprouting angiogenesis, Fimbrial protein PapE, Anti-CEA 79 single chain Fv, natural killer cell inhibitory signaling pathway, HLA class I histocompatibility antigen, A-11 alpha chain, positive regulation of T cell apoptotic process, Sulfur oxidation protein SoxZ, sorocarp development, T cell receptor alpha variable 12-3, membrane depolarization during cardiac muscle cell action potential, Pap fimbrial major pilin protein, extrinsic apoptotic signaling pathway, H-2 class I histocompatibility antigen, Q10 alpha chain, Ig gamma-1 chain C region secreted form, modulation by host of viral RNA genome replication, positive regulation by host of viral genome replication, circadian regulation of gene expression, -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2., Phosphotyrosine phosphatase. PTPase., transmembrane receptor protein tyrosine phosphatase signaling pathway, Equus caballus, Mucosal addressin cell adhesion molecule 1, integrin binding involved in cell-matrix adhesion, Listeria monocytogenes EGD-e, Major histocompatibility complex class I-related gene protein, negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, negative regulation of dendritic cell differentiation, positive regulation of apoptotic process, 1,4-alpha-glucan branching enzyme activity, Amylo-(1,4 to 1,6)transglucosidase. Amylo-(1,4->1,6)-transglycosylase. Branching enzyme. Glycogen branching enzyme., ATP + protein L-histidine = ADP + protein N-phospho-L-histidine., negative regulation of protein secretion, regulation of neuron migration, insulin-like growth factor binding, positive regulation of insulin receptor signaling pathway, Macaca mulatta, response to interferon-gamma, Sialic acid-binding Ig-like lectin 7, positive regulation of MAP kinase activity, Avicelase. Beta-1,4-endoglucan hydrolase. Beta-1,4-glucanase. Carboxymethyl cellulase. Celludextrinase. Endo-1,4-beta-D-glucanase. Endo-1,4-beta-D-glucanohydrolase. Endo-1,4-beta-glucanase. Endoglucanase., axonogenesis, female courtship behavior, filopodium, T-cell receptor beta-2 chain C region, synapse organization, T cell receptor alpha variable 22, embryonic hemopoiesis, stimulatory C-type lectin receptor signaling pathway, Interferon regulatory factor 3, protein domain specific binding, establishment of viral latency, regulation of monocyte differentiation, brain-derived neurotrophic factor receptor signaling pathway, nerve growth factor signaling pathway, Major histocompatibility complex class Ib M10.5, in utero embryonic development, inner ear morphogenesis, lung-associated mesenchyme development, mesenchymal cell differentiation, negative regulation of transcription from RNA polymerase II promoter, orbitofrontal cortex development, vacuolar phosphate transport, ATP + a protein = ADP + a phosphoprotein., Protein phosphokinase. Protein serine kinase. Protein serine-threonine kinase. Protein-serine kinase. Serine kinase. Serine protein kinase. Serine(threonine) protein kinase. Serine-specific protein kinase. Serine/threonine protein kinase. Threonine-specific protein kinase., cardiac muscle hypertrophy, protein kinase A signaling, positive regulation of B cell proliferation, regulation of transcription, DNA-templated, chromatin binding, defense response, liver development, negative regulation of extrinsic apoptotic signaling pathway, response to bacterium, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, Ig gamma-2A chain C region, membrane-bound form, endosome to lysosome transport, multivesicular body, positive regulation of endocytosis, growth factor binding, interleukin-6-mediated signaling pathway, positive regulation of cardiac muscle hypertrophy, response to lead ion, Coxsackievirus and adenovirus receptor, homotypic cell-cell adhesion, Uncharacterized protein, ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., Hsp90 protein binding, cellular response to vascular endothelial growth factor stimulus, Streptococcus pneumoniae TIGR4, regulation of fatty acid biosynthetic process, negative regulation of mast cell degranulation, VH coding region, T cell receptor beta variable 20-1, sarcomerogenesis, Bacillus subtilis subsp. subtilis str. 168, negative regulation of tumor necrosis factor superfamily cytokine production, Shigella flexneri, HLA class I histocompatibility antigen, B-15 alpha chain, CSF1-CSF1R complex, protein complex assembly, Down syndrome cell adhesion molecule 1, isoform BE, phagocytosis, regulation of axonogenesis, regulation of dendrite morphogenesis, Interleukin-21 receptor, Sulfolobus solfataricus, FimH, transport, Streptococcus agalactiae 2603V/R, Growth hormone receptor, cellular calcium ion homeostasis, endoplasmic reticulum organization, zinc ion binding, humoral immune response mediated by circulating immunoglobulin, proteolysis, Golgi apparatus, antigen processing and presentation of peptide antigen via MHC class I, focal adhesion, negative regulation of receptor binding, positive regulation of ferrous iron import across plasma membrane, positive regulation of protein binding, positive regulation of receptor-mediated endocytosis, Fc-gamma receptor signaling pathway involved in phagocytosis, blood microparticle, Ornithorhynchus anatinus, positive regulation of endothelial cell proliferation, T cell costimulation, bud elongation involved in lung branching, epidermis morphogenesis, fibroblast growth factor receptor signaling pathway involved in hemopoiesis, fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow, lung alveolus development, regulation of morphogenesis of a branching structure, squamous basal epithelial stem cell differentiation involved in prostate gland acinus development, membrane fusion, HLA class I histocompatibility antigen, B-41 alpha chain, regulation of phosphatidylinositol 3-kinase signaling, skeletal system morphogenesis, RNA binding, T cell receptor binding, type I interferon signaling pathway, Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3)., extrinsic component of cytoplasmic side of plasma membrane, hair follicle morphogenesis, protein-glutamine gamma-glutamyltransferase activity, transferase activity, transferring acyl groups, antigen processing and presentation of exogenous peptide antigen via MHC class I, Immunoglobulin heavy constant epsilon, intracellular membrane-bounded organelle, regulation of interferon-gamma-mediated signaling pathway, protein C-terminus binding, Ras guanyl-nucleotide exchange factor activity, Natural cytotoxicity triggering receptor 2, Beta-galactosidase., defense response to virus, external side of plasma membrane, protein homodimerization activity, HLA class II histocompatibility antigen, DR beta 5 chain, HLA class I histocompatibility antigen, B-35 alpha chain, negative regulation of phosphatase activity, Immunoglobulin alpha Fc receptor, cellular response to interleukin-6, Neopullulanase., -!- Surface-associated subtilisin-like serine peptidase with very specific substrate specificity. -!- Virulent strains of streptococci, including Streptococcus pyogenes, can evade human detection and phagocytosis by destroying the complement chemotaxin C5a. -!- Cleavage of human C5a by this enzyme reduces the ability of C5a to bind receptors on the surface of polymorphonuclear neutrophil leukocytes (PMNLs) and thereby abolishes its chemotactic properties. -!- Belongs to peptidase family S8A., Putative alkaline amylopullulanase, F30C7 light chain variable region, Cell adhesion molecule 1, Golgi-associated vesicle membrane, Polycystin-1, anatomical structure morphogenesis, metanephric ascending thin limb development, metanephric collecting duct development, p53 binding, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptide hormone secretion, FixG-related protein, Fimbrial subunit type 1, Endoglucanase J, Streptomyces avermitilis MA-4680 = NBRC 14893, chloroplast, starch metabolic process, Herpes simplex virus (type 1 / strain 17), cell projection, neuromuscular junction development, retina development in camera-type eye, Pseudomonas aeruginosa, Bacillus sp., proteasome-mediated ubiquitin-dependent protein catabolic process, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, muscle organ development, branching involved in labyrinthine layer morphogenesis, Immunoevasin, myosin light chain kinase activity, Dystroglycan, epithelial tube branching involved in lung morphogenesis, microtubule cytoskeleton, positive regulation of cytokine production, regulation of tolerance induction dependent upon immune response, heterotypic cell-cell adhesion, T cell differentiation in thymus, cellular response to granulocyte macrophage colony-stimulating factor stimulus, integral component of plasma membrane, interleukin-16 receptor activity, maintenance of protein location in cell, membrane organization, positive regulation of kinase activity, regulation of defense response to virus by virus, transcription initiation from RNA polymerase II promoter, negative regulation of cell division, Chaperone CupB2, otolith morphogenesis, Alpha amylase, catalytic region, lens morphogenesis in camera-type eye, H-2 class II histocompatibility antigen, A-K beta chain, Guanine-7-methyltransferase. Messenger ribonucleate guanine 7-methyltransferase. Messenger RNA guanine 7-methyltransferase., mRNA (guanine-N(7)-)-methyltransferase., positive regulation of monocyte chemotactic protein-1 production, Intercellular adhesion molecule 3, T-helper 17 cell lineage commitment, Interferon-gamma binding protein C4R, negative regulation of T cell apoptotic process, cAMP metabolic process, positive regulation of establishment of protein localization to plasma membrane, response to growth factor, MHC, interleukin-22 binding, interleukin-22 receptor activity, arterial endothelial cell fate commitment, T-cell gamma protein, Hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains., HLA class II histocompatibility antigen, DM beta chain, Low affinity immunoglobulin gamma Fc region receptor II-b, -!- Specific for (1->6)-alpha-D-glucans (dextrans) and, unlike cyclomaltodextrin glucanotransferase (EC 2.4.1.19), without activity toward (1->4)-alpha-D-glucans, such as amylose. -!- It also has no activity on oligosaccharides, such as amylopectin and pullulan, containing (1->6)-alpha-D-glucosidic linkages at branch points. -!- The enzyme from Bacillus circulans T-3040 has been shown to form cycloisomalto-oligosaccharides of three sizes (7, 8 and 9 glucose units). -!- It will also catalyze the disproportionation of two isomalto- oligosaccharides molecules to yield a series of isomalto- oligosachharides and the addition of D-glucose to cycloisomalto- oligosaccharides with ring opening to form isomalto-oligosaccharides., Xyloglucan-specific endo-beta-1,4-glucanase., HLA-DMA protein, Killer cell immunoglobulin-like receptor 2DS2, Nuclear factor of activated T-cells 5, negative regulation of smoothened signaling pathway, Protein FimF, Palladin, Clostridium perfringens, Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limit dextrins., alpha-beta T cell activation involved in immune response, Ig kappa chain V-V region MOPC 149, extrinsic component of membrane, cellulose 1,4-beta-cellobiosidase activity, Golgi cisterna, S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)- ubiquitinyl-[acceptor protein]-L-lysine., H-2 class II histocompatibility antigen, E-B beta chain, Bacteroides intestinalis DSM 17393, Variable region-containing chitin-binding protein 3, Exopolygalacturonase, long-term synaptic potentiation, postsynaptic membrane, visual learning, Ig heavy chain V region J539, collagen metabolic process, elastic fiber assembly, Obscurin, endothelial cell morphogenesis, Thermotoga neapolitana DSM 4359, regulation of peptidyl-tyrosine phosphorylation, MHC class I alpha chain 2, regulation of ventricular cardiac muscle cell membrane repolarization, clathrin-coated endocytic vesicle, CMRF35-like molecule 8, negative regulation of MyD88-dependent toll-like receptor signaling pathway, negative regulation of eosinophil migration, Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds., Saccharophagus degradans 2-40, interleukin-7 receptor activity, Bacteroides vulgatus ATCC 8482, connexin binding, Kluyveromyces lactis NRRL Y-1140, Interferon lambda receptor 1, platelet-derived growth factor beta-receptor activity, high-density lipoprotein particle, intermediate-density lipoprotein particle, lipoprotein particle, memory, negative regulation of excitatory postsynaptic potential, negative regulation of synapse structural plasticity, positive regulation of cellular response to thapsigargin, protein dimerization activity, myelin sheath, response to folic acid, podosome, primary amine oxidase activity, virus tail, tube, Glutamicibacter protophormiae, cell morphogenesis, regulation of cell size, T-cell surface glycoprotein CD1c, Ig heavy chain V region 3, positive regulation of neuron differentiation, alpha-actinin binding, Maltogenic alpha-amylase, intercellular bridge, Signal-regulatory protein beta-1 isoform 3, replicative cell aging, sn-glycero-3-phosphocholine + H(2)O = choline + sn-glycerol 3-phosphate., Natural cytotoxicity triggering receptor 1, Sperm-specific class P protein 19, Vh gene product, HLA class I histocompatibility antigen B-57, myeloid dendritic cell activation, natural killer cell activation involved in immune response, glucuronoside catabolic process, Major sperm protein isoform alpha, -!- These enzymes can also remove the 5-phosphate from Ins(1,4,5)P(3) and/or Ins(1,3,4,5)P(4). -!- They are a diverse family of enzymes, with differing abilities to catalyze two or more of the four reactions listed. -!- They are thought to use inositol lipids rather than inositol phosphates as substrates in vivo. -!- All of them can use either or both of PtdIns(4,5)P(2) and PtdIns(3,4,5)P(3) as substrates; this is the main property that distinguishes them from EC 3.1.3.56., 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl- 1D-myo-inositol 4-phosphate + phosphate., Diphosphoinositide phosphatase. Inositol 1,4,5-triphosphate 5-phosphomonoesterase. Inositol triphosphate 5-phosphomonoesterase. IP(3) phosphatase. Phosphatidyl-inositol-bisphosphate phosphatase. Phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase. Phosphatidylinositol 4,5-bisphosphate phosphatase. Phosphatidylinositol-bisphosphatase. Polyphosphoinositol lipid 5-phosphatase. PtdIns(4,5)P(2) phosphatase. Triphosphoinositide phosphatase. Triphosphoinositide phosphomonoesterase. Type II inositol polyphosphate 5-phosphatase. Type II inositol-1,4,5-trisphosphate 5-phosphatase., GTPase activator activity, Phosphoinositide 5-phosphatase., Dextranase, carnitine shuttle, filamin binding, negative regulation of T cell receptor signaling pathway, cilium assembly, establishment of protein localization, platelet activation, small GTPase binding, positive regulation of axon extension, dendrite guidance, embryonic heart tube development, Receptor-type tyrosine-protein phosphatase S, multicellular organism development, Ig gamma chain C region, Neural cell adhesion molecule 2, 1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic, Glucoamylase, Ig kappa chain V-III region MOPC 63, protein transport, platelet alpha granule, Interference hedgehog, hedgehog family protein binding, Paenibacillus polymyxa, Escherichia coli APEC O1, Ig kappa chain V-V region MOPC 21, membrane depolarization, Ig kappa chain V-V region HP 124E1, negative regulation of interleukin-12 production, Anopheles gambiae, Thioester-containing protein 1, Fibronectin type III domain-containing protein 5, lateral inhibition, Escherichia coli ETEC H10407, Protein fimH, H-2 class II histocompatibility antigen, E-D alpha chain, positive regulation of hyaluronan biosynthetic process, Tenascin-X, histone acetyltransferase complex, mitochondrion organization, protein stabilization, positive regulation of peptidyl-tyrosine phosphorylation, regulation of immunoglobulin production, Antifreeze protein, T-cell receptor gamma chain C region 1, Down syndrome cell adhesion molecule 1, isoform AM, Ig gamma-2A chain C region, A allele, Putative inner membrane protein, negative regulation of smooth muscle cell proliferation, positive regulation of granulocyte macrophage colony-stimulating factor production, Bacteroides fragilis NCTC 9343, Putative beta-galactosidase, Ig heavy chain V region 36-65, positive regulation of immunoglobulin secretion, blood vessel development, positive regulation of CD4-positive, alpha-beta T cell proliferation, monomeric IgA immunoglobulin complex, hyperosmotic response, detection of chemical stimulus involved in sensory perception of bitter taste, cleavage furrow, Amyloid lambda 6 light chain variable region PIP, regulation of sodium ion transmembrane transporter activity, sodium ion transmembrane transport, voltage-gated sodium channel complex, negative regulation of collagen biosynthetic process, regulation of cell projection organization, sperm mitochondrion organization, Fibronectin binding protein, larval visceral muscle development, regulation of myoblast fusion, axon target recognition, negative regulation of homophilic cell adhesion, T-cell surface glycoprotein CD1e, membrane-associated, Anti-human Fc gamma receptor III 3G8 gamma heavy chain variable region, Golgi organization, Ancillary protein 1, peptidyl-tyrosine dephosphorylation, Measles virus strain Edmonston, negative regulation of interferon-beta production, 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase., negative regulation of interferon-gamma biosynthetic process, negative regulation of interleukin-10 secretion, positive regulation of muscle cell differentiation, negative regulation of insulin receptor signaling pathway, Interleukin-20 receptor subunit alpha, Cytotoxic and regulatory T-cell molecule, basal lamina, Hemoglobin subunit beta-2, erythrocyte development, Protein-glutamine gamma-glutamyltransferase 2, negative regulation of endoplasmic reticulum calcium ion concentration, antigen processing and presentation of peptide antigen, Junctional adhesion molecule A, actomyosin structure organization, Tenascin, Vascular endothelial growth factor receptor 1, actin cytoskeleton, Lmo2446 protein, axon extension, establishment of glial blood-brain barrier, IgG H chain, cell-cell signaling, collateral sprouting, azurophil granule membrane, detection of mechanical stimulus involved in sensory perception of sound, developmental pigmentation, lamellipodium assembly, lymphoid progenitor cell differentiation, myeloid leukocyte differentiation, negative regulation of programmed cell death, cellular response to peptide hormone stimulus, positive regulation of pri-miRNA transcription from RNA polymerase II promoter, response to UV-B, ubiquitin protein ligase binding, regulation of type I interferon production, presynaptic membrane organization, T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, establishment of endothelial barrier, positive regulation of cellular extravasation, Escherichia coli UTI89, nerve growth factor receptor activity, protein complex involved in cell adhesion, cell death, positive regulation of parathyroid hormone secretion, Putative fimbriae assembly chaparone, regulation of endothelial cell apoptotic process, Major sperm protein isoform beta, Ig kappa chain V-III region PC 3741/TEPC 111, Killer cell immunoglobulin-like receptor 2DL2, Pagrus major, histone H4-K8 acetylation, skeletal muscle thin filament assembly, renal system development, Beta-chain, Rhamnogalacturonan endolyase YesW, laminin receptor activity, SLAM family member 5, homophilic cell adhesion via plasma membrane adhesion molecules, positive regulation of apoptotic cell clearance, regulation of triglyceride biosynthetic process, Ictalurus punctatus, 28 kDa outer membrane protein Omp28, lymph node development, negative regulation of inflammatory response, Drosophila melanogaster, central nervous system morphogenesis, dendrite, mushroom body development, cAMP-dependent protein kinase complex, positive regulation of interleukin-12 production, COPII-coated vesicle budding, ER to Golgi vesicle-mediated transport, modulation by virus of host morphology or physiology, positive regulation of viral genome replication, myeloid dendritic cell differentiation, Glycogenase., interleukin-13 receptor complex, interferon receptor activity, negative regulation of cell proliferation, Tapasin, endoplasmic reticulum-Golgi intermediate compartment membrane, Vascular endothelial growth factor receptor 2, endosome, positive regulation of endothelial cell migration, vascular endothelial growth factor-activated receptor activity, mesodermal cell differentiation, nail development, endogenous lipid antigen binding, regulation of immature T cell proliferation in thymus, Filamin-C, Two-component system sensor histidine kinase, lactation, periplasmic space, growth hormone receptor signaling pathway, response to cycloheximide, Natural cytotoxicity triggering receptor 3 ligand 1, Complement C4-A, leukocyte tethering or rolling, Hordeum vulgare, Fc receptor mediated inhibitory signaling pathway, T cell proliferation involved in immune response, regulation of T cell activation, immunoglobulin complex, circulating, positive regulation of type I hypersensitivity, Cyclomaltodextrin glucanotransferase, Cyclomaltodextrin glucanotransferase., Gingipain R2, calcium ion binding, Ig heavy chain V region 345, Streptococcus agalactiae A909, animal organ regeneration, cellular response to inorganic substance, cellular response to molecule of bacterial origin, neuronal cell body, basolateral plasma membrane, cell junction, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, intercalated disc, neuromuscular junction, Fc receptor signaling pathway, specific granule membrane, Escherichia coli, Protein-glutamine gamma-glutamyltransferase E, T-cell receptor beta-1 chain C region, B cell receptor signaling pathway, Nuclear factor of activated T-cells, cytoplasmic 2, negative regulation of apoptotic process, positive regulation of NF-kappaB transcription factor activity, neutrophil chemotaxis, antibody-dependent cellular cytotoxicity, ciliary neurotrophic factor receptor binding, ciliary neurotrophic factor receptor complex, response to cytokine, fibroblast growth factor binding, fibroblast growth factor receptor signaling pathway, regulation of osteoblast differentiation, interleukin-1 receptor activity, Hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains., Golgi medial cisterna, beta-2-microglobulin binding, Malto-oligosyltrehalose trehalohydrolase, -!- Cf. EC 3.2.1.41 and EC 3.2.1.57., Hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose)., Thermoactinomyces vulgaris, SCP. Streptococcal C5a peptidase., I band, actin filament binding, condensed nuclear chromosome, skeletal muscle myosin thick filament assembly, Ig heavy chain V region RF, negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I, Anti-deoxynivalenol scFv lambda heavy chain variable region, Actinomyces viscosus, Bacillus metalloendopeptidase. Bacillus subtilis neutral proteinase. Megateriopeptidase., Ig-like repeat domain protein 3, O-GlcNAcase NagJ, dorsal/ventral axon guidance, Arabidopsis thaliana, Colletotrichum graminicola M1.001, TRAV14D-2, response to axon injury, LigB, blood coagulation, positive regulation of platelet-derived growth factor receptor signaling pathway, positive regulation of protein kinase B signaling, ER to Golgi transport vesicle membrane, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, branch elongation involved in salivary gland morphogenesis, coronal suture morphogenesis, embryonic digestive tract morphogenesis, gland morphogenesis, multicellular organism growth, positive regulation of cell division, positive regulation of epithelial cell proliferation, post-embryonic development, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, regulation of epithelial cell proliferation, HADV38S2, morphogenesis of an epithelial sheet, VH7183-DSP2-JH3-CH1 protein, negative regulation of innate immune response, negative regulation of interleukin-6 production, CD8 alpha antigen, Mature alpha chain of major histocompatibility complex class I antigen, ScFv B8E5 protein, chaperone-mediated protein folding, pilus, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cellular protein metabolic process, complement activation, serine-type endopeptidase activity, Chitinase., Fc-epsilon receptor signaling pathway, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent, positive regulation of cell proliferation, positive regulation of fibroblast proliferation, regulation of protein phosphorylation, late endosome membrane, polysaccharide assembly with MHC class II protein complex, T cell mediated immunity, cellular defense response, cellular response to iron(III) ion, phagocytic vesicle membrane, positive regulation of I-kappaB kinase/NF-kappaB signaling, alpha-beta T cell receptor complex, HLA class I histocompatibility antigen, B-52 alpha chain, endocardium development, epithelial to mesenchymal transition involved in endocardial cushion formation, positive regulation of ephrin receptor signaling pathway, regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, ventricular trabecula myocardium morphogenesis, Fervidolysin, LOC500183 protein, cellular response to glucose starvation, postsynaptic density, type 1 fibroblast growth factor receptor binding, cornification, cornified envelope, Agrobacterium fabrum str. C58, Ig heavy chain V region MOPC 104E, Cycloisomaltooligosaccharide glucanotransferase., Interleukin-18 receptor accessory protein, -!- The enzyme from Aspergillus aculeatus is specific for xyloglucan and does not hydrolyze other cell-wall components. -!- The reaction involves endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues., xyloglucan-specific endo-beta-1,4-glucanase activity, negative regulation of natural killer cell activation, Dickeya chrysanthemi, germinal center formation, astrocyte development, Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids., Thermus thermophilus HB27, Proto-oncogene c-Rel, Interleukin-3 receptor subunit alpha, negative regulation of protein oligomerization, positive regulation of ER to Golgi vesicle-mediated transport, -!- The RING domain of E3 ubiquitin transferase serves as a mediator bringing the ubiquitin-charged E2 ubiquitin-conjugating enzyme and the acceptor protein together to enable the direct transfer of ubiquitin through the formation of an isopeptide bond between the C-terminal glycine residue of ubiquitin an the epsilon-amino group of an L-lysine residue of the acceptor protein. -!- The RING-E3 domain does not form a catalytic thioester intermediate with ubiquitin (unlike the HECT domain, EC 2.3.2.26). -!- RING-type ubiquitin transferases may occur as single-chain enzymes but also in dimeric forms or in multi-subunit assemblies. -!- Formerly EC 6.3.2.19 and EC 6.3.2.21., Probable E3 ubiquitin-protein ligase MID2, phosphoprotein binding, MHC class 1, Leucine-rich repeat-containing protein 4C, Oncorhynchus mykiss, Platelet glycoprotein VI, tetraspanin-enriched microdomain, imaginal disc-derived wing vein morphogenesis, wing disc dorsal/ventral pattern formation, genitalia development, mesonephric tubule development, rough endoplasmic reticulum, activation of protein kinase B activity, Myosin light chain kinase, smooth muscle, Triggering receptor expressed on myeloid cells 2, platelet-derived growth factor receptor signaling pathway, amyloid fibril formation, negative regulation of protein localization to nucleus, Hyalophora cecropia, Ig gamma-2A chain C region, VH186.2-D-J-C mu protein, cell growth, negative regulation of fibroblast proliferation, negative regulation of T cell activation, Killer cell immunoglobulin-like receptor 2DL4, Pan troglodytes, T cell receptor beta variable 28, positive regulation of interleukin-2 production, Pseudomonas aeruginosa PAO1, positive regulation of Notch signaling pathway, T-cell receptor alpha chain V region 2B4, Anti-human Langerin 2G3 lambda chain, response to lipid, nematode larval development, positive regulation of vulval development, regulation of cell fate specification, Anoxybacillus sp. LM18-11, response to stress, regulation of lamellipodium assembly, negative regulation of anoikis, RNA polymerase II repressing transcription factor binding, Recombining binding protein suppressor of hairless, transcriptional repressor complex, peptidyl-serine phosphorylation, uncultured bacterium 35A20, Kin of IRRE-like protein 1, positive regulation of alpha-beta T cell proliferation, pentameric IgM immunoglobulin complex, negative regulation of JAK-STAT cascade, Type 1 fimbiral adhesin FimH, mRNA guanylyltransferase., T-cell receptor beta chain V region E1, SH3 domain binding, gamma-catenin binding, negative regulation of platelet-derived growth factor receptor signaling pathway, phosphatase activity, immunoglobulin secretion involved in immune response, Interferon gamma receptor 2, Roundabout 1, Roundabout signaling pathway, muscle cell cellular homeostasis, vesicle, negative regulation of interferon-alpha production, Killer cell immunoglobulin-like receptor 2DS4, centrosome localization, neural tube development, semaphorin receptor activity, somitogenesis, lipid metabolic process, regulation of small GTPase mediated signal transduction, trans-Golgi network, Hydrolysis of (1->6)-alpha-D-glucosidic linkages in pullulan, amylopectin and glycogen, and in the alpha- and beta-limit dextrins of amylopectin and glycogen., Pullulanase., actin binding, Myb complex, adenylate cyclase-inhibiting dopamine receptor signaling pathway, cytoplasmic sequestering of protein, positive regulation of integrin-mediated signaling pathway, protein localization to plasma membrane, B9-scFv, positive regulation of canonical Wnt signaling pathway, transcription regulatory region sequence-specific DNA binding, retina layer formation, Roundabout homolog 1, negative regulation of chemokine-mediated signaling pathway, Fimbrial protein, Oryza sativa Japonica Group, Semaphorin-7A, Ig kappa chain V-III region PC 7183, Quinohemoprotein amine dehydrogenase 60 kDa subunit, response to cadmium ion, Antigen receptor, negative regulation of Notch signaling pathway, positive regulation of cell motility, positive regulation of protein tyrosine kinase activity, epithelial cell differentiation, Fibronectin type 3 and ankyrin repeat domains 1 protein, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, titin binding, negative regulation of axonogenesis, Ig heavy chain V region J558, BRE, negative regulation of guanyl-nucleotide exchange factor activity, negative regulation of hydrogen peroxide-mediated programmed cell death, Nuclear factor of activated T-cells, cytoplasmic 4, carbohydrate metabolic process, ephrin receptor signaling pathway, actin filament bundle assembly, HLA class II histocompatibility antigen, DP beta 1 chain, epidermal cell fate specification, multicellular organismal protein metabolic process, positive regulation of brood size, extrinsic apoptotic signaling pathway in absence of ligand, HLA class I histocompatibility antigen, B-8 alpha chain, Two-component system sensor histidine kinase/response regulator, hybrid (One-component system), dermatan sulfate catabolic process, disaccharide metabolic process, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, Streptomyces coelicolor A3(2), Host cell factor 1, interleukin-12 alpha subunit binding, Programmed cell death 1 ligand 2, H2-Ab1 protein, Human herpesvirus 5 strain AD169, Killer cell immunoglobulin-like receptor 2DL1, secretory dimeric IgA immunoglobulin complex, bone morphogenesis, transport vesicle, Dictyostelium discoideum, actin cytoskeleton organization, response to cAMP, positive regulation of regulatory T cell differentiation, osteoblast differentiation, syndecan binding, H-2 class II histocompatibility antigen, A-D alpha chain, Canis lupus familiaris, regulation of atrial cardiac muscle cell membrane depolarization, Immunoglobulin kappa variable 1D-33, negative regulation of alkaline phosphatase activity, semaphorin-plexin signaling pathway, Signal-regulatory protein gamma, Streptomyces venezuelae, Alpha-trypsin. Beta-trypsin., Down syndrome cell adhesion molecule 1, isoform AO, Tyrosine-protein phosphatase Lar, oogenesis, Killer cell immunoglobulin-like receptor 3DL1, Nectin-2, protein localization to Golgi apparatus, Beta-glucosidase., bicellular tight junction assembly, Ig heavy chain V region PJ14, intracellular signal transduction, Cellulase., Endoglucanase, Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans., axon ensheathment, interleukin-12 receptor binding, regulation of cytokine biosynthetic process, regulation of tyrosine phosphorylation of STAT protein, sexual reproduction, ovarian follicle development, pigmentation, RNA polymerase II distal enhancer sequence-specific DNA binding, cellular response to hydrogen peroxide, response to organic substance, tumor necrosis factor-mediated signaling pathway, negative regulation of type I interferon production, RNA polymerase II core promoter sequence-specific DNA binding, regulation of adaptive immune response, apoptotic process involved in luteolysis, BDNF/NT-3 growth factors receptor, cellular response to nerve growth factor stimulus, interleukin-10 receptor activity, cytokine biosynthetic process, negative regulation of gene expression, positive regulation of interleukin-10 production, positive regulation of mitotic nuclear division, branching involved in salivary gland morphogenesis, lung development, positive regulation of cell cycle, regulation of extrinsic apoptotic signaling pathway in absence of ligand, regulation of lateral mesodermal cell fate specification, spermatogenesis, interleukin-6 binding, positive regulation of chemokine production, Geobacillus stearothermophilus, Carcinoembryonic antigen-related cell adhesion molecule 1, negative regulation of platelet aggregation, Ig heavy chain Mem5, B cell receptor complex, PH domain binding, core promoter binding, starch binding, Rhamnogalacturonan endolyase., Intimin, mitochondrion, olfactory bulb development, protein phosphatase binding, BMP receptor binding, myoblast fusion, neuron migration, positive regulation of natural killer cell mediated cytotoxicity, positive thymic T cell selection, ankyrin binding, protection from natural killer cell mediated cytotoxicity, HLA class I histocompatibility antigen, A-24 alpha chain, melanotic encapsulation of foreign target, nerve maturation, pleated septate junction, septate junction, immunoglobulin receptor binding, RT1 class I histocompatibility antigen, AA alpha chain, Coagulation factor XIII A chain, protein localization to synapse, signal transducer activity, downstream of receptor, Down syndrome cell adhesion molecule 1, isoform AP, Tcell receptor chain, CD166 antigen, immunological synapse, intrinsic component of plasma membrane, MHC class I receptor activity, dendritic cell differentiation, negative regulation of T cell mediated cytotoxicity, negative regulation of T cell proliferation, negative regulation of cytokine secretion involved in immune response, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of cytolysis, protein phosphatase 1 binding, microtubule organizing center, positive regulation of actin cytoskeleton reorganization, regulation of vascular permeability, sprouting angiogenesis, blood coagulation, fibrin clot formation, -!- Also hydrolyzes linear maltodextrin. -!- Formerly EC 3.2.1.12 and EC 3.2.1.13., Exocyst complex component 2, oxygen binding, apoptotic cell clearance, ORF492, Immunoglobulin kappa variable 4-1, cellular response to hepatocyte growth factor stimulus, response to muramyl dipeptide, Granulocyte colony-stimulating factor receptor, regulation of myeloid cell differentiation, oncostatin-M-mediated signaling pathway, calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules, multicellular organismal response to stress, positive regulation of cardiac muscle cell proliferation, actin cytoskeleton reorganization, adherens junction, cell-cell adherens junction, epithelial structure maintenance, HLA class II histocompatibility antigen, DQ alpha 1 chain, -!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112., Receptor protein tyrosine kinase., Receptor protein-tyrosine kinase., cell cortex, cytoplasm, phosphatidylinositol-mediated signaling, protein autophosphorylation, negative regulation of interleukin-18 production, secretory granule lumen, Myomesin-1, kinase binding, Signal-regulatory protein beta-1, fibrillar center, regulation of CD4-positive, alpha-beta T cell activation, response to wounding, histone binding, MHC class I protein binding, regulation of gene expression, regulation of protein complex stability, unfolded protein binding, axon extension involved in axon guidance, Bacteroides thetaiotaomicron VPI-5482, Beta-mannosidase, -!- Chitosan is a partially or totally N-deacetylated chitin derivative that is found in the cell walls of some phytopathogenic fungi and comprises D-glucosamine residues with a variable content of GlcNAc residues. -!- Acts specifically on chitooligosaccharides and chitosan, having maximal activity on chitotetraose, chitopentaose and their corresponding alcohols. -!- Can degrade GlcN-GlcNAc but not GlcNAc-GlcNAc., regulation of cell shape, transmembrane receptor protein tyrosine kinase activity, Receptor-type tyrosine-protein phosphatase delta, protein dephosphorylation, hemidesmosome, receptor complex, Chaperone protein caf1M, embryo implantation, maltodextrin transport, cellular response to hormone stimulus, receptor internalization, endoplasmic reticulum unfolded protein response, negative regulation by host of viral genome replication, Transcription factor RelB, regulation of erythrocyte differentiation, T-cell surface glycoprotein CD4, endoplasmic reticulum membrane, entry into host cell, enzyme binding, induction by virus of host cell-cell fusion, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, antigen binding, cellular response to iron ion, endoplasmic reticulum lumen, positive regulation of receptor binding, specific granule lumen, Serratia marcescens, Oryctolagus cuniculus, activation of plasma proteins involved in acute inflammatory response, cell surface, extracellular matrix, positive regulation of angiogenesis, positive regulation of cell migration, HLA class II histocompatibility antigen, DR alpha chain, antigen processing and presentation of exogenous peptide antigen via MHC class II, cognition, peptide antigen binding, endoplasmic reticulum exit site, positive regulation of interferon-gamma production, positive regulation of memory T cell activation, protein heterotetramerization, outer membrane-bounded periplasmic space, cell adhesion, mannose binding, endoplasmic reticulum, endodermal cell differentiation, extracellular matrix disassembly, interaction with other organism via secreted substance involved in symbiotic interaction, T-cell receptor alpha chain V region PHDS58, Cytokine receptor common subunit beta, protein tyrosine kinase activity, respiratory gaseous exchange, beta-galactosidase complex, Lymphocyte function-associated antigen 3, leukocyte migration, negative regulation of neuron projection development, cytokine metabolic process, positive regulation of oxidative stress-induced cell death, tertiary granule membrane, Neopullulanase 2, The primary cleavage site is at 67-His-|-Lys-68 in human C5a with a minor secondary cleavage site at 58-Ala-|-Ser-59., M band, Non-specific serine/threonine protein kinase., striated muscle thin filament, T-lymphocyte activation antigen CD86, Ig heavy chain V region B1-8/186-2, transcription factor activity, sequence-specific DNA binding