PDB Information

PDB6UVY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints.
Winneroski, L.L., Erickson, J.A., Green, S.J., Lopez, J.E., Stout, S.L., Porter, W.J., Timm, D.E., Audia, J.E., Barberis, M., Beck, J.P., Boggs, L.N., Borders, A.R., Boyer, R.D., Brier, R.A., Hembre, E.J., Hendle, J., Garcia-Losada, P., Minguez, J.M., Mathes, B.M., May, P.C., Monk, S.A., Rankovic, Z., Shi, Y., Watson, B.M., Yang, Z., Mergott, D.J.
Bioorg.Med.Chem.
HeaderHydrolase/Inhibitor
Released2019-11-04
Resolution1.710
CATH Insert Date15 Dec, 2019

PDB Images (1)

PDB Prints

PDB Chains (0)

Chain ID Date inserted into CATH CATH Status

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description