Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche, C.C., Henderson, R., Hsu, A., Behrens, S., Chen, X., Zhou, T., Wiehe, K., Saunders, K.O., Alam, S.M., Bonsignori, M., Borgnia, M.J., Sattentau, Q.J., Eaton, A., Greene, K., Gao, H., Liao, H.X., Williams, W.B., Peacock, J., Tang, H., Perez, L.G., Edwards, R.J., Kepler, T.B., Korber, B.T., Kwong, P.D., Mascola, J.R., Acharya, P., Haynes, B.F., Montefiori, D.C.
Plos Pathog.