PDB Information

PDB6T2W
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The discovery of 7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one (AZD7648), a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor.
Goldberg, F.W., Finlay, M.R.V., Ting, A., Beattie, D., Lamont, G., Fallan, C., Wrigley, G., Schimpl, M., Howard, M.R., Williamson, B., Vazquez-Chantada, M., Barratt, D., Davies, B., Cadogan, E., Ramos Montoya, A., Dean, E.
J.Med.Chem.
HeaderTransferase
Released2019-10-09
Resolution1.700
CATH Insert Date05 Jan, 2020

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Chain ID Date inserted into CATH CATH Status

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Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description