Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma.
Munck Af Rosenschold, M., Johannesson, P., Nikitidis, A., Tyrchan, C., Chang, H.F., Ronn, R., Chapman, D., Ullah, V., Nikitidis, G., Glader, P., Kack, H., Bonn, B., Wagberg, F., Bjorkstrand, E., Andersson, U., Swedin, L., Rohman, M., Andreasson, T., Bergstrom, E.L., Jiang, F., Zhou, X.H., Lundqvist, A.J., Malmberg, A., Ek, M., Gordon, E., Pettersen, A., Ripa, L., Davis, A.M.
J.Med.Chem.