PDB 6r2e
PDB Information
| PDB | 6R2E |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation | Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R.
Biomolecules
|
| Header | Transferase |
| Released | 2019-03-16 |
| Resolution | 2.550 |
| CATH Insert Date | 14 Apr, 2019 |
PDB Images (17)
6r2e
PDB 6r2e
6r2eA
PDB Chain 6r2eA
6r2eB
PDB Chain 6r2eB
6r2eC
PDB Chain 6r2eC
6r2eD
PDB Chain 6r2eD
6r2eE
PDB Chain 6r2eE
6r2eF
PDB Chain 6r2eF
6r2eG
PDB Chain 6r2eG
6r2eH
PDB Chain 6r2eH
6r2eA00
CATH Domain 6r2eA00
6r2eB00
CATH Domain 6r2eB00
6r2eC00
CATH Domain 6r2eC00
6r2eD00
CATH Domain 6r2eD00
6r2eE00
CATH Domain 6r2eE00
6r2eF00
CATH Domain 6r2eF00
6r2eG00
CATH Domain 6r2eG00
6r2eH00
CATH Domain 6r2eH00
PDB Prints
PDB Chains (8)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Apr, 2019 | Chopped |
| B | 14 Apr, 2019 | Chopped |
| C | 14 Apr, 2019 | Chopped |
| D | 14 Apr, 2019 | Chopped |
| E | 14 Apr, 2019 | Chopped |
| F | 14 Apr, 2019 | Chopped |
| G | 14 Apr, 2019 | Chopped |
| H | 14 Apr, 2019 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6r2eA00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eB00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eC00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eD00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eE00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eF00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eG00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
| 6r2eH00 | 15 Apr, 2019 | 3.30.572.10 | Assigned |
UniProtKB Entries (8)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |