PDB Information

PDB6QMT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.
Karki, R.G., Powers, J., Mainolfi, N., Anderson, K., Belanger, D.B., Liu, D., Ji, N., Jendza, K., Gelin, C.F., Mac Sweeney, A., Solovay, C., Delgado, O., Crowley, M., Liao, S.M., Argikar, U.A., Flohr, S., La Bonte, L.R., Lorthiois, E.L., Vulpetti, A., Brown, A., Long, D., Prentiss, M., Gradoux, N., de Erkenez, A., Cumin, F., Adams, C., Jaffee, B., Mogi, M.
J.Med.Chem.
HeaderHydrolase
Released2019-02-08
Resolution1.800
CATH Insert Date28 Apr, 2019

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Apr, 2019 Chopped
B 28 Apr, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6qmtA01 29 Apr, 2019 2.40.10.10 Assigned
6qmtA02 29 Apr, 2019 2.40.10.10 Assigned
6qmtB01 29 Apr, 2019 2.40.10.10 Assigned
6qmtB02 29 Apr, 2019 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D
P00746 CFAD_HUMAN Homo sapiens Complement factor D
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