PDB 6q2w

PDB Information

PDB6Q2W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active ROR gamma inverse agonists.
Amaudrut, J., Argiriadi, M.A., Barth, M., Breinlinger, E.C., Bressac, D., Broqua, P., Calderwood, D.J., Chatar, M., Cusack, K.P., Gauld, S.B., Jacquet, S., Kamath, R.V., Kort, M.E., Lepais, V., Luccarini, J.M., Masson, P., Montalbetti, C., Mounier, L., Potin, D., Poupardin, O., Rouaud, S., Spitzer, L., Wallace, C.D.
Bioorg.Med.Chem.Lett.
HeaderTranscription
Released2018-12-03
Resolution1.990
CATH Insert Date02 Jun, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 02 Jun, 2019 Chopped
B 02 Jun, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6q2wA00 03 Jun, 2019 1.10.565.10 Assigned
6q2wB00 03 Jun, 2019 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma