PDB 6plg

PDB Information

PDB6PLG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.
Mullarky, E., Xu, J., Robin, A.D., Huggins, D.J., Jennings, A., Noguchi, N., Olland, A., Lakshminarasimhan, D., Miller, M., Tomita, D., Michino, M., Su, T., Zhang, G., Stamford, A.W., Meinke, P.T., Kargman, S., Cantley, L.C.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Inhibitor
Released2019-06-30
Resolution2.930
CATH Insert Date04 Aug, 2019

PDB Images (9)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 04 Aug, 2019 New
B 04 Aug, 2019 New
C 04 Aug, 2019 New
D 04 Aug, 2019 New
E 04 Aug, 2019 New
F 04 Aug, 2019 New
G 04 Aug, 2019 New
H 04 Aug, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description