PDB 6o8u

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Overview

PDB Information

PDB	6O8U
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. Bryan, M.C., Drobnick, J., Gobbi, A., Kolesnikov, A., Chen, Y., Rajapaksa, N., Ndubaku, C., Feng, J., Chang, W., Francis, R., Yu, C., Choo, E.F., DeMent, K., Ran, Y., An, L., Emson, C., Huang, Z., Sujatha-Bhaskar, S., Brightbill, H., DiPasquale, A., Maher, J., Wai, J., McKenzie, B.S., Lupardus, P.J., Zarrin, A.A., Kiefer, J.R. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2019-03-12
Resolution	1.800
CATH Insert Date	26 May, 2019

PDB Images (5)

Image of CATH 6o8u

6o8u

PDB 6o8u

Image of CATH 6o8uA

6o8uA

PDB Chain 6o8uA

Image of CATH 6o8uB

6o8uB

PDB Chain 6o8uB

Image of CATH 6o8uC

6o8uC

PDB Chain 6o8uC

Image of CATH 6o8uD

6o8uD

PDB Chain 6o8uD

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	26 May, 2019	Holding pen
B	26 May, 2019	Holding pen
C	26 May, 2019	Holding pen
D	26 May, 2019	Holding pen

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4
Q9NWZ3	IRAK4_HUMAN	Homo sapiens	Interleukin-1 receptor-associated kinase 4