PDB Information

PDB6O3A
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Raman, S., Beilschmidt, M., To, M., Lin, K., Lui, F., Jmeian, Y., Ng, M., Fernandez, M., Fu, Y., Mascall, K., Duque, A., Wang, X., Pan, G., Angers, S., Moffat, J., Sidhu, S.S., Magram, J., Sinclair, A.M., Fransson, J., Julien, J.P.
Proc. Natl. Acad. Sci. U.S.A.
HeaderSignaling Protein
Released2019-02-26
Resolution2.100
CATH Insert Date07 Apr, 2019

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Holding pen
E 07 Apr, 2019 Holding pen

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6o3aA01 08 Apr, 2019 2.60.40.10 Assigned
6o3aA02 08 Apr, 2019 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O75084 FZD7_HUMAN Homo sapiens Frizzled-7