PDB Information

PDB6NZR
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.
Wrobleski, S.T., Moslin, R., Lin, S., Zhang, Y., Spergel, S., Kempson, J., Tokarski, J.S., Strnad, J., Zupa-Fernandez, A., Cheng, L., Shuster, D., Gillooly, K., Yang, X., Heimrich, E., McIntyre, K.W., Chaudhry, C., Khan, J., Ruzanov, M., Tredup, J., Mulligan, D., Xie, D., Sun, H., Huang, C., D'Arienzo, C., Aranibar, N., Chiney, M., Chimalakonda, A., Pitts, W.J., Lombardo, L., Carter, P.H., Burke, J.R., Weinstein, D.S.
J.Med.Chem.
HeaderTransferase
Released2019-02-14
Resolution2.560
CATH Insert Date04 Aug, 2019

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 04 Aug, 2019 New
B 04 Aug, 2019 New

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (0)

Accession Gene ID Taxon Description
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