PDB Information

PDB6NW2
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group.
Hamilton, G.L., Chen, H., Deshmukh, G., Eigenbrot, C., Fong, R., Johnson, A., Kohli, P.B., Lupardus, P.J., Liederer, B.M., Ramaswamy, S., Wang, H., Wang, J., Xu, Z., Zhu, Y., Vucic, D., Patel, S.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2019-02-05
Resolution2.000
CATH Insert Date05 May, 2019

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2019 Chopped
B 05 May, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6nw2A01 06 May, 2019 3.30.200.20 Assigned
6nw2A02 06 May, 2019 1.10.510.10 Assigned
6nw2B01 06 May, 2019 3.30.200.20 Assigned
6nw2B02 06 May, 2019 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q13546 RIPK1_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 1
Q13546 RIPK1_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 1