PDB Information

PDB6NPI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEpstein-Barr virus (strain B95-8)
Primary Citation
Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Messick, T.E., Smith, G.R., Soldan, S.S., McDonnell, M.E., Deakyne, J.S., Malecka, K.A., Tolvinski, L., van den Heuvel, A.P.J., Gu, B.W., Cassel, J.A., Tran, D.H., Wassermann, B.R., Zhang, Y., Velvadapu, V., Zartler, E.R., Busson, P., Reitz, A.B., Lieberman, P.M.
Sci Transl Med
HeaderViral Protein/Inhibitor
Released2019-01-17
Resolution1.500
CATH Insert Date24 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2019 Chopped
B 24 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6npiA00 25 Mar, 2019 3.30.70.390 Assigned
6npiB00 25 Mar, 2019 3.30.70.390 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03211 EBNA1_EBVB9 Human herpesvirus 4 strain B95-8 Epstein-Barr nuclear antigen 1
P03211 EBNA1_EBVB9 Human herpesvirus 4 strain B95-8 Epstein-Barr nuclear antigen 1