PDB Information

PDB6NNA
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Martin, M.W., Lancia Jr., D.R., Li, H., Schiller, S.E.R., Toms, A.V., Wang, Z., Bair, K.W., Castro, J., Fessler, S., Gotur, D., Hubbs, S.E., Kauffman, G.S., Kershaw, M., Luke, G.P., McKinnon, C., Yao, L., Lu, W., Millan, D.S.
Bioorg. Med. Chem. Lett.
HeaderTransferase
Released2019-01-14
Resolution2.260
CATH Insert Date24 Feb, 2019

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Feb, 2019 Chopped
B 24 Feb, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6nnaA01 25 Feb, 2019 Holding pen
6nnaA02 25 Feb, 2019 3.40.50.720 Assigned
6nnaB01 25 Feb, 2019 Holding pen
6nnaB02 25 Feb, 2019 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
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