PDB 6nh8

PDB Information

PDB6NH8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-12-21
Resolution1.800
CATH Insert Date17 Mar, 2019

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped
C 17 Mar, 2019 Chopped
D 17 Mar, 2019 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6nh8A01 18 Mar, 2019 3.90.340.10 Assigned
6nh8A02 18 Mar, 2019 3.90.440.10 Assigned
6nh8A03 18 Mar, 2019 3.90.1230.10 Assigned
6nh8B01 18 Mar, 2019 3.90.340.10 Assigned
6nh8B02 18 Mar, 2019 3.90.440.10 Assigned
6nh8B03 18 Mar, 2019 3.90.1230.10 Assigned
6nh8C01 18 Mar, 2019 3.90.340.10 Assigned
6nh8C02 18 Mar, 2019 3.90.440.10 Assigned
6nh8C03 18 Mar, 2019 3.90.1230.10 Assigned
6nh8D01 18 Mar, 2019 3.90.340.10 Assigned
6nh8D02 18 Mar, 2019 3.90.440.10 Assigned
6nh8D03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
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