PDB Information

PDB6N1S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceToxoplasma gondii
Primary Citation
Discovery of Selective Toxoplasma gondii Dihydrofolate Reductase Inhibitors for the Treatment of Toxoplasmosis.
Hopper, A.T., Brockman, A., Wise, A., Gould, J., Barks, J., Radke, J.B., Sibley, L.D., Zou, Y., Thomas, S.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-11-11
Resolution3.000
CATH Insert Date27 Jan, 2019

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 27 Jan, 2019 Holding pen
B 27 Jan, 2019 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
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