PDB 6n1h
PDB Information
| PDB | 6N1H |
| Method | ELECTRON MICROSCOPY |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A.
|
| Header | Signaling Protein |
| Released | 2018-11-08 |
| Resolution | 3.170 |
| CATH Insert Date | 16 Dec, 2018 |
PDB Images (33)
6n1h
PDB 6n1h
6n1hA
PDB Chain 6n1hA
6n1hB
PDB Chain 6n1hB
6n1hC
PDB Chain 6n1hC
6n1hD
PDB Chain 6n1hD
6n1hE
PDB Chain 6n1hE
6n1hF
PDB Chain 6n1hF
6n1hG
PDB Chain 6n1hG
6n1hH
PDB Chain 6n1hH
6n1hI
PDB Chain 6n1hI
6n1hJ
PDB Chain 6n1hJ
6n1hK
PDB Chain 6n1hK
6n1hL
PDB Chain 6n1hL
6n1hM
PDB Chain 6n1hM
6n1hN
PDB Chain 6n1hN
6n1hO
PDB Chain 6n1hO
6n1hP
PDB Chain 6n1hP
6n1hA00
CATH Domain 6n1hA00
6n1hB00
CATH Domain 6n1hB00
6n1hC00
CATH Domain 6n1hC00
6n1hD00
CATH Domain 6n1hD00
6n1hE00
CATH Domain 6n1hE00
6n1hF00
CATH Domain 6n1hF00
6n1hG00
CATH Domain 6n1hG00
6n1hH00
CATH Domain 6n1hH00
6n1hI00
CATH Domain 6n1hI00
6n1hJ00
CATH Domain 6n1hJ00
6n1hK00
CATH Domain 6n1hK00
6n1hL00
CATH Domain 6n1hL00
6n1hM00
CATH Domain 6n1hM00
6n1hN00
CATH Domain 6n1hN00
6n1hO00
CATH Domain 6n1hO00
6n1hP00
CATH Domain 6n1hP00
PDB Prints
PDB Chains (16)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Dec, 2018 | Chopped |
| B | 16 Dec, 2018 | Chopped |
| C | 16 Dec, 2018 | Chopped |
| D | 16 Dec, 2018 | Chopped |
| E | 16 Dec, 2018 | Chopped |
| F | 16 Dec, 2018 | Chopped |
| G | 16 Dec, 2018 | Chopped |
| H | 16 Dec, 2018 | Chopped |
| I | 16 Dec, 2018 | Chopped |
| J | 16 Dec, 2018 | Chopped |
| K | 16 Dec, 2018 | Chopped |
| L | 16 Dec, 2018 | Chopped |
| M | 16 Dec, 2018 | Chopped |
| N | 16 Dec, 2018 | Chopped |
| O | 16 Dec, 2018 | Chopped |
| P | 16 Dec, 2018 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6n1hA00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hB00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hC00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hD00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hE00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hF00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hG00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hH00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hI00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hJ00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hK00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hL00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hM00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hN00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hO00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
| 6n1hP00 | 28 Feb, 2019 | 1.10.533.10 | Assigned |
UniProtKB Entries (16)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |
| Q9ULZ3 | ASC_HUMAN | Homo sapiens | Apoptosis-associated speck-like protein containing a CARD |