PDB Information

PDB6MQ3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme.
Maianti, J.P., Tan, G.A., Vetere, A., Welsh, A.J., Wagner, B.K., Seeliger, M.A., Liu, D.R.
Nat.Chem.Biol.
HeaderHydrolase/Hydrolase Inhibitor
Released2018-10-09
Resolution3.570
CATH Insert Date07 Apr, 2019

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6mq3A01 08 Apr, 2019 3.30.830.10 Assigned
6mq3A02 08 Apr, 2019 3.30.830.10 Assigned
6mq3A03 08 Apr, 2019 3.30.830.10 Assigned
6mq3A04 08 Apr, 2019 3.30.830.10 Assigned
6mq3B01 08 Apr, 2019 3.30.830.10 Assigned
6mq3B02 08 Apr, 2019 3.30.830.10 Assigned
6mq3B03 08 Apr, 2019 3.30.830.10 Assigned
6mq3B04 08 Apr, 2019 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme