PDB Information

PDB6MKS
MethodELECTRON MICROSCOPY
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
Matyszewski, M., Zheng, W., Lueck, J., Antiochos, B., Egelman, E.H., Sohn, J.
J. Biol. Chem.
HeaderProtein Fibril
Released2018-09-26
Resolution3.400
CATH Insert Date16 Dec, 2018

PDB Images (63)

PDB Prints

PDB Chains (31)

Chain ID Date inserted into CATH CATH Status
a 16 Dec, 2018 Chopped
A 16 Dec, 2018 Chopped
b 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped
c 16 Dec, 2018 Chopped
C 16 Dec, 2018 Chopped
d 16 Dec, 2018 Chopped
D 16 Dec, 2018 Chopped
e 16 Dec, 2018 Chopped
E 16 Dec, 2018 Chopped
F 16 Dec, 2018 Chopped
G 16 Dec, 2018 Chopped
H 16 Dec, 2018 Chopped
I 16 Dec, 2018 Chopped
J 16 Dec, 2018 Chopped
K 16 Dec, 2018 Chopped
L 16 Dec, 2018 Chopped
M 16 Dec, 2018 Chopped
N 16 Dec, 2018 Chopped
O 16 Dec, 2018 Chopped
P 16 Dec, 2018 Chopped
Q 16 Dec, 2018 Chopped
R 16 Dec, 2018 Chopped
S 16 Dec, 2018 Chopped
T 16 Dec, 2018 Chopped
U 16 Dec, 2018 Chopped
V 16 Dec, 2018 Chopped
W 16 Dec, 2018 Chopped
X 16 Dec, 2018 Chopped
Y 16 Dec, 2018 Chopped
Z 16 Dec, 2018 Chopped

CATH Domains (31)

Domain ID Date inserted into CATH Superfamily CATH Status
6mksa00 28 Feb, 2019 Holding pen
6mksA00 28 Feb, 2019 Holding pen
6mksb00 28 Feb, 2019 Holding pen
6mksB00 28 Feb, 2019 Holding pen
6mksc00 28 Feb, 2019 Holding pen
6mksC00 28 Feb, 2019 Holding pen
6mksd00 28 Feb, 2019 Holding pen
6mksD00 28 Feb, 2019 Holding pen
6mkse00 28 Feb, 2019 Holding pen
6mksE00 28 Feb, 2019 Holding pen
6mksF00 28 Feb, 2019 Holding pen
6mksG00 28 Feb, 2019 Holding pen
6mksH00 28 Feb, 2019 Holding pen
6mksI00 28 Feb, 2019 Holding pen
6mksJ00 28 Feb, 2019 Holding pen
6mksK00 28 Feb, 2019 Holding pen
6mksL00 28 Feb, 2019 Holding pen
6mksM00 28 Feb, 2019 Holding pen
6mksN00 28 Feb, 2019 Holding pen
6mksO00 28 Feb, 2019 Holding pen
6mksP00 28 Feb, 2019 Holding pen
6mksQ00 28 Feb, 2019 Holding pen
6mksR00 28 Feb, 2019 Holding pen
6mksS00 28 Feb, 2019 Holding pen
6mksT00 28 Feb, 2019 Holding pen
6mksU00 28 Feb, 2019 Holding pen
6mksV00 28 Feb, 2019 Holding pen
6mksW00 28 Feb, 2019 Holding pen
6mksX00 28 Feb, 2019 Holding pen
6mksY00 28 Feb, 2019 Holding pen
6mksZ00 28 Feb, 2019 Holding pen

UniProtKB Entries (31)

Accession Gene ID Taxon Description
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4