PDB 6mdd

PDB Links
Overview

PDB Information

PDB	6MDD
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. Bagdanoff, J.T., Chen, Z., Acker, M., Chen, Y.N., Chan, H., Dore, M., Firestone, B., Fodor, M., Fortanet, J., Hentemann, M., Kato, M., Koenig, R., LaBonte, L.R., Liu, S., Mohseni, M., Ntaganda, R., Sarver, P., Smith, T., Sendzik, M., Stams, T., Spence, S., Towler, C., Wang, H., Wang, P., Williams, S.L., LaMarche, M.J. J. Med. Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2018-09-04
Resolution	2.050
CATH Insert Date	17 Feb, 2019

PDB Images (9)

Image of CATH 6mdd

6mdd

PDB 6mdd

Image of CATH 6mddA

6mddA

PDB Chain 6mddA

Image of CATH 6mddB

6mddB

PDB Chain 6mddB

Image of CATH 6mddA01

6mddA01

CATH Domain 6mddA01

Image of CATH 6mddA02

6mddA02

CATH Domain 6mddA02

Image of CATH 6mddA03

6mddA03

CATH Domain 6mddA03

Image of CATH 6mddB01

6mddB01

CATH Domain 6mddB01

Image of CATH 6mddB02

6mddB02

CATH Domain 6mddB02

Image of CATH 6mddB03

6mddB03

CATH Domain 6mddB03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	17 Feb, 2019	Chopped
B	17 Feb, 2019	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6mddA01	18 Feb, 2019	3.30.505.10	Assigned
6mddA02	18 Feb, 2019	3.30.505.10	Assigned
6mddA03	18 Feb, 2019	3.90.190.10	Assigned
6mddB01	18 Feb, 2019	3.30.505.10	Assigned
6mddB02	18 Feb, 2019	3.30.505.10	Assigned
6mddB03	18 Feb, 2019	3.90.190.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q06124	PTN11_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 11
Q06124	PTN11_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 11