PDB Information

PDB6I4B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourcePlasmodium falciparum
Primary Citation
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Pippione, A.C., Sainas, S., Goyal, P., Fritzson, I., Cassiano, G.C., Giraudo, A., Giorgis, M., Tavella, T.A., Bagnati, R., Rolando, B., Caing-Carlsson, R., Costa, F.T.M., Andrade, C.H., Al-Karadaghi, S., Boschi, D., Friemann, R., Lolli, M.L.
Eur J Med Chem
HeaderOxidoreductase
Released2018-11-09
Resolution1.980
CATH Insert Date23 Dec, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2018 Chopped
B 23 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6i4bA00 27 Dec, 2018 3.20.20.70 Assigned
6i4bB00 27 Dec, 2018 3.20.20.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08210 PYRD_PLAF7 Plasmodium falciparum 3D7 Dihydroorotate dehydrogenase (quinone), mitochondrial
Q08210 PYRD_PLAF7 Plasmodium falciparum 3D7 Dihydroorotate dehydrogenase (quinone), mitochondrial