PDB Information

PDB6I3U
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington's Disease Models.
Toledo-Sherman, L., Breccia, P., Cachope, R., Bate, J.R., Angulo-Herrera, I., Wishart, G., Matthews, K.L., Martin, S.L., Cox, H.C., McAllister, G., Penrose, S.D., Vater, H., Esmieu, W., Van de Poel, A., Van de Bospoort, R., Strijbosch, A., Lamers, M., Leonard, P., Jarvis, R.E., Blackaby, W., Barnes, K., Eznarriaga, M., Dowler, S., Smith, G.D., Fischer, D.F., Lazari, O., Yates, D., Rose, M., Jang, S.W., Munoz-Sanjuan, I., Dominguez, C.
J.Med.Chem.
HeaderLyase
Released2018-11-07
Resolution2.090
CATH Insert Date24 Mar, 2019

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2019 Write scan list

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8NEB9 PK3C3_HUMAN Homo sapiens Phosphatidylinositol 3-kinase catalytic subunit type 3