PDB 6htp

PDB Links
Overview

PDB Information

PDB	6HTP
Method	X-RAY DIFFRACTION
Host Organism	Saccharomyces cerevisiae S288c
Gene Source	Homo sapiens
Primary Citation	Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. Xin, B.T., Huber, E.M., de Bruin, G., Heinemeyer, W., Maurits, E., Espinal, C., Du, Y., Janssens, M., Weyburne, E.S., Kisselev, A.F., Florea, B.I., Driessen, C., van der Marel, G.A., Groll, M., Overkleeft, H.S. J.Med.Chem.
Header	Hydrolase
Released	2018-10-04
Resolution	3.000
CATH Insert Date	03 Feb, 2019

PDB Images (57)

6htp

PDB 6htp

6htpa

PDB Chain 6htpa

6htpA

PDB Chain 6htpA

6htpb

PDB Chain 6htpb

6htpB

PDB Chain 6htpB

6htpC

PDB Chain 6htpC

6htpD

PDB Chain 6htpD

6htpE

PDB Chain 6htpE

6htpF

PDB Chain 6htpF

6htpG

PDB Chain 6htpG

6htpH

PDB Chain 6htpH

6htpI

PDB Chain 6htpI

6htpJ

PDB Chain 6htpJ

6htpK

PDB Chain 6htpK

6htpL

PDB Chain 6htpL

6htpM

PDB Chain 6htpM

6htpN

PDB Chain 6htpN

6htpO

PDB Chain 6htpO

6htpP

PDB Chain 6htpP

6htpQ

PDB Chain 6htpQ

6htpR

PDB Chain 6htpR

6htpS

PDB Chain 6htpS

6htpT

PDB Chain 6htpT

6htpU

PDB Chain 6htpU

6htpV

PDB Chain 6htpV

6htpW

PDB Chain 6htpW

6htpX

PDB Chain 6htpX

6htpY

PDB Chain 6htpY

6htpZ

PDB Chain 6htpZ

6htpa00

CATH Domain 6htpa00

6htpA00

CATH Domain 6htpA00

6htpb00

CATH Domain 6htpb00

6htpB00

CATH Domain 6htpB00

6htpC00

CATH Domain 6htpC00

6htpD00

CATH Domain 6htpD00

6htpE00

CATH Domain 6htpE00

6htpF00

CATH Domain 6htpF00

6htpG00

CATH Domain 6htpG00

6htpH00

CATH Domain 6htpH00

6htpI00

CATH Domain 6htpI00

6htpJ00

CATH Domain 6htpJ00

6htpK00

CATH Domain 6htpK00

6htpL00

CATH Domain 6htpL00

6htpM00

CATH Domain 6htpM00

6htpN00

CATH Domain 6htpN00

6htpO00

CATH Domain 6htpO00

6htpP00

CATH Domain 6htpP00

6htpQ00

CATH Domain 6htpQ00

6htpR00

CATH Domain 6htpR00

6htpS00

CATH Domain 6htpS00

6htpT00

CATH Domain 6htpT00

6htpU00

CATH Domain 6htpU00

6htpV00

CATH Domain 6htpV00

6htpW00

CATH Domain 6htpW00

6htpX00

CATH Domain 6htpX00

6htpY00

CATH Domain 6htpY00

6htpZ00

CATH Domain 6htpZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	03 Feb, 2019	Chopped
A	03 Feb, 2019	Chopped
b	03 Feb, 2019	Chopped
B	03 Feb, 2019	Chopped
C	03 Feb, 2019	Chopped
D	03 Feb, 2019	Chopped
E	03 Feb, 2019	Chopped
F	03 Feb, 2019	Chopped
G	03 Feb, 2019	Chopped
H	03 Feb, 2019	Chopped
I	03 Feb, 2019	Chopped
J	03 Feb, 2019	Chopped
K	03 Feb, 2019	Chopped
L	03 Feb, 2019	Chopped
M	03 Feb, 2019	Chopped
N	03 Feb, 2019	Chopped
O	03 Feb, 2019	Chopped
P	03 Feb, 2019	Chopped
Q	03 Feb, 2019	Chopped
R	03 Feb, 2019	Chopped
S	03 Feb, 2019	Chopped
T	03 Feb, 2019	Chopped
U	03 Feb, 2019	Chopped
V	03 Feb, 2019	Chopped
W	03 Feb, 2019	Chopped
X	03 Feb, 2019	Chopped
Y	03 Feb, 2019	Chopped
Z	03 Feb, 2019	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6htpa00	04 Feb, 2019	3.60.20.10	Assigned
6htpA00	04 Feb, 2019	3.60.20.10	Assigned
6htpb00	04 Feb, 2019	3.60.20.10	Assigned
6htpB00	04 Feb, 2019	3.60.20.10	Assigned
6htpC00	04 Feb, 2019	3.60.20.10	Assigned
6htpD00	04 Feb, 2019	3.60.20.10	Assigned
6htpE00	04 Feb, 2019	3.60.20.10	Assigned
6htpF00	04 Feb, 2019	3.60.20.10	Assigned
6htpG00	04 Feb, 2019	3.60.20.10	Assigned
6htpH00	04 Feb, 2019	3.60.20.10	Assigned
6htpI00	04 Feb, 2019	3.60.20.10	Assigned
6htpJ00	04 Feb, 2019	3.60.20.10	Assigned
6htpK00	04 Feb, 2019	3.60.20.10	Assigned
6htpL00	04 Feb, 2019	3.60.20.10	Assigned
6htpM00	04 Feb, 2019	3.60.20.10	Assigned
6htpN00	04 Feb, 2019	3.60.20.10	Assigned
6htpO00	04 Feb, 2019	3.60.20.10	Assigned
6htpP00	04 Feb, 2019	3.60.20.10	Assigned
6htpQ00	04 Feb, 2019	3.60.20.10	Assigned
6htpR00	04 Feb, 2019	3.60.20.10	Assigned
6htpS00	04 Feb, 2019	3.60.20.10	Assigned
6htpT00	04 Feb, 2019	3.60.20.10	Assigned
6htpU00	04 Feb, 2019	3.60.20.10	Assigned
6htpV00	04 Feb, 2019	3.60.20.10	Assigned
6htpW00	04 Feb, 2019	3.60.20.10	Assigned
6htpX00	04 Feb, 2019	3.60.20.10	Assigned
6htpY00	04 Feb, 2019	3.60.20.10	Assigned
6htpZ00	04 Feb, 2019	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4