PDB Information

PDB6HSK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Marek, M., Shaik, T.B., Heimburg, T., Chakrabarti, A., Lancelot, J., Ramos-Morales, E., Da Veiga, C., Kalinin, D., Melesina, J., Robaa, D., Schmidtkunz, K., Suzuki, T., Holl, R., Ennifar, E., Pierce, R.J., Jung, M., Sippl, W., Romier, C.
J. Med. Chem.
HeaderHydrolase
Released2018-10-01
Resolution2.100
CATH Insert Date16 Dec, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6hskA00 28 Feb, 2019 3.40.800.20 Assigned
6hskB00 28 Feb, 2019 3.40.800.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9BY41 HDAC8_HUMAN Homo sapiens Histone deacetylase 8
Q9BY41 HDAC8_HUMAN Homo sapiens Histone deacetylase 8