PDB Information

PDB6HRW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Primary Citation
A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Prevet, H., Moune, M., Tanina, A., Kemmer, C., Herledan, A., Frita, R., Wohlkonig, A., Bourotte, M., Villemagne, B., Leroux, F., Gitzinger, M., Baulard, A.R., Deprez, B., Wintjens, R., Willand, N., Flipo, M.
Eur J Med Chem
HeaderDna Binding Protein
Released2018-09-28
Resolution2.450
CATH Insert Date03 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Mar, 2019 Chopped
B 03 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6hrwA00 04 Mar, 2019 Holding pen
6hrwB00 04 Mar, 2019 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O53623 O53623_MYCTU Mycobacterium tuberculosis H37Rv Probable transcriptional regulatory protein
O53623 O53623_MYCTU Mycobacterium tuberculosis H37Rv Probable transcriptional regulatory protein