PDB Information

PDB6HMN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides.
Waszkowycz, B., Smith, K.M., McGonagle, A.E., Jordan, A.M., Acton, B., Fairweather, E.E., Griffiths, L.A., Hamilton, N.M., Hamilton, N.S., Hitchin, J.R., Hutton, C.P., James, D.I., Jones, C.D., Jones, S., Mould, D.P., Small, H.F., Stowell, A.I.J., Tucker, J.A., Waddell, I.D., Ogilvie, D.J.
J.Med.Chem.
HeaderHydrolase
Released2018-09-12
Resolution2.870
CATH Insert Date16 Dec, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6hmnA00 28 Feb, 2019 Holding pen

UniProtKB Entries (0)

Accession Gene ID Taxon Description