PDB 6hm0

PDB Information

PDB6HM0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7.
Zoppi, V., Hughes, S.J., Maniaci, C., Testa, A., Gmaschitz, T., Wieshofer, C., Koegl, M., Riching, K.M., Daniels, D.L., Spallarossa, A., Ciulli, A.
J.Med.Chem.
HeaderTranscription
Released2018-09-11
Resolution2.400
CATH Insert Date20 Jan, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Jan, 2019 Chopped
B 20 Jan, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6hm0A00 21 Jan, 2019 1.20.920.10 Assigned
6hm0B00 21 Jan, 2019 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9H8M2 BRD9_HUMAN Homo sapiens Bromodomain-containing protein 9
Q9H8M2 BRD9_HUMAN Homo sapiens Bromodomain-containing protein 9