PDB Information

PDB6HCW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceCryptosporidium parvum (strain Iowa II)
Primary Citation
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Baragana, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J.A., Pisco, J.P., Peet, C., Dranow, D.M., Robinson, D.A., Jansen, C., Norcross, N.R., Vinayak, S., Anderson, M., Brooks, C.F., Cooper, C.A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T.E., Hallyburton, I., Horst, B.G., Hulverson, M.A., Ferguson, L., Jimenez-Diaz, M.B., Jumani, R.S., Lorimer, D.D., Love, M.S., Maher, S., Matthews, H., McNamara, C.W., Miller, P., O'Neill, S., Ojo, K.K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L.M., Scullion, P., Sharma, A., Shepherd, S.M., Shishikura, Y., Simeons, F.R.C., Stebbins, E.E., Stojanovski, L., Straschil, U., Tamaki, F.K., Tamjar, J., Torrie, L.S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F.J., Maser, P., Kyle, D.E., Winzeler, E.A., Myler, P.J., Wyatt, P.G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C.D., Gray, D.W., Fairlamb, A.H., Pisliakov, A.V., Walpole, C., Read, K.D., Van Voorhis, W.C., Gilbert, I.H.
Proc.Natl.Acad.Sci.USA
HeaderTransferase
Released2018-08-16
Resolution1.460
CATH Insert Date07 Apr, 2019

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6hcwA01 08 Apr, 2019 2.40.50.140 Assigned
6hcwA02 08 Apr, 2019 3.30.930.10 Assigned
6hcwB01 08 Apr, 2019 2.40.50.140 Assigned
6hcwB02 08 Apr, 2019 3.30.930.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q5CR27 Q5CR27_CRYPI Cryptosporidium parvum Iowa II Lysine--tRNA ligase
Q5CR27 Q5CR27_CRYPI Cryptosporidium parvum Iowa II Lysine--tRNA ligase