PDB Information

PDB6GL8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Casara, P., Davidson, J., Claperon, A., Le Toumelin-Braizat, G., Vogler, M., Bruno, A., Chanrion, M., Lysiak-Auvity, G., Le Diguarher, T., Starck, J.B., Chen, I., Whitehead, N., Graham, C., Matassova, N., Dokurno, P., Pedder, C., Wang, Y., Qiu, S., Girard, A.M., Schneider, E., Grave, F., Studeny, A., Guasconi, G., Rocchetti, F., Maiga, S., Henlin, J.M., Colland, F., Kraus-Berthier, L., Le Gouill, S., Dyer, M.J.S., Hubbard, R., Wood, M., Amiot, M., Cohen, G.M., Hickman, J.A., Morris, E., Murray, J., Geneste, O.
Oncotarget
HeaderApoptosis
Released2018-05-23
Resolution1.400
CATH Insert Date16 Dec, 2018

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P10415 BCL2_HUMAN Homo sapiens Apoptosis regulator Bcl-2
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
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