PDB Information

PDB6FMF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
Powell, J., Mota, F., Steadman, D., Soudy, C., Miyauchi, J.T., Crosby, S., Jarvis, A., Reisinger, T., Winfield, N., Evans, G., Finniear, A., Yelland, T., Chou, Y.T., Chan, A.W.E., O'Leary, A., Cheng, L., Liu, D., Fotinou, C., Milagre, C., Martin, J.F., Jia, H., Frankel, P., Djordjevic, S., Tsirka, S.E., Zachary, I.C., Selwood, D.L.
J. Med. Chem.
HeaderSignaling Protein
Released2018-01-31
Resolution2.810
CATH Insert Date16 Dec, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6fmfA00 28 Feb, 2019 2.60.120.260 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14786 NRP1_HUMAN Homo sapiens Neuropilin-1