PDB Information

PDB6FGB
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.
Smith, B., Kiessling, A., Lledo-Garcia, R., Dixon, K.L., Christodoulou, L., Catley, M.C., Atherfold, P., D'Hooghe, L.E., Finney, H., Greenslade, K., Hailu, H., Kevorkian, L., Lightwood, D., Meier, C., Munro, R., Qureshi, O., Sarkar, K., Shaw, S.P., Tewari, R., Turner, A., Tyson, K., West, S., Shaw, S., Brennan, F.R.
MAbs
HeaderImmune System
Released2018-01-10
Resolution2.900
CATH Insert Date02 Sep, 2018

PDB Images (10)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2018 Chopped
B 02 Sep, 2018 Chopped
H 02 Sep, 2018 Holding pen
L 02 Sep, 2018 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
6fgbA01 03 Sep, 2018 3.30.500.10 Assigned
6fgbA02 03 Sep, 2018 2.60.40.10 Assigned
6fgbB00 03 Sep, 2018 2.60.40.10 Assigned
6fgbL01 03 Sep, 2018 2.60.40.10 Assigned
6fgbL02 03 Sep, 2018 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P55899 FCGRN_HUMAN Homo sapiens IgG receptor FcRn large subunit p51
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin