PDB Information

PDB6FCF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors.
Yang, B., Vasbinder, M.M., Hird, A.W., Su, Q., Wang, H., Yu, Y., Toader, D., Lyne, P.D., Read, J.A., Breed, J., Ioannidis, S., Deng, C., Grondine, M., DeGrace, N., Whitston, D., Brassil, P., Janetka, J.W.
J. Med. Chem.
HeaderTransferase
Released2017-12-20
Resolution1.850
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6fcfA01 29 Jun, 2018 3.30.200.20 Assigned
6fcfA02 29 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1