PDB 6f78

PDB Information

PDB6F78
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid.
Pippione, A.C., Carnovale, I.M., Bonanni, D., Sini, M., Goyal, P., Marini, E., Pors, K., Adinolfi, S., Zonari, D., Festuccia, C., Wahlgren, W.Y., Friemann, R., Bagnati, R., Boschi, D., Oliaro-Bosso, S., Lolli, M.L.
Eur J Med Chem
HeaderOxidoreductase
Released2017-12-07
Resolution1.300
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6f78A00 29 Jun, 2018 3.20.20.100 Assigned
6f78B00 29 Jun, 2018 3.20.20.100 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3