PDB 6ezx

PDB Information

PDB6EZX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
Giroud, M., Dietzel, U., Anselm, L., Banner, D., Kuglstatter, A., Benz, J., Blanc, J.B., Gaufreteau, D., Liu, H., Lin, X., Stich, A., Kuhn, B., Schuler, F., Kaiser, M., Brun, R., Schirmeister, T., Kisker, C., Diederich, F., Haap, W.
J. Med. Chem.
HeaderHydrolase
Released2017-11-16
Resolution2.340
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6ezxA00 29 Jun, 2018 3.90.70.10 Assigned
6ezxB00 29 Jun, 2018 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1
P07711 CATL1_HUMAN Homo sapiens Cathepsin L1