PDB 6eds

PDB Information

PDB6EDS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme.
Maianti, J.P., Tan, G.A., Vetere, A., Welsh, A.J., Wagner, B.K., Seeliger, M.A., Liu, D.R.
Nat.Chem.Biol.
HeaderHydrolase/Inhibitor
Released2018-08-10
Resolution3.180
CATH Insert Date07 Apr, 2019

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Chopped
C 07 Apr, 2019 Rejected
D 07 Apr, 2019 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6edsA01 08 Apr, 2019 3.30.830.10 Assigned
6edsA02 08 Apr, 2019 3.30.830.10 Assigned
6edsA03 08 Apr, 2019 3.30.830.10 Assigned
6edsA04 08 Apr, 2019 3.30.830.10 Assigned
6edsB01 08 Apr, 2019 3.30.830.10 Assigned
6edsB02 08 Apr, 2019 3.30.830.10 Assigned
6edsB03 08 Apr, 2019 3.30.830.10 Assigned
6edsB04 08 Apr, 2019 3.30.830.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P01275 GLUC_HUMAN Homo sapiens Glucagon
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P01275 GLUC_HUMAN Homo sapiens Glucagon