PDB Information

PDB6E9L
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceBos taurus
Primary Citation
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure Based Drug Design.
Hobson, A.D., Judge, R.A., Aguirre, A.L., Brown, B.S., Cui, Y., Ding, P., Dominguez, E., DiGiammarino, E., Egan, D.A., Freiberg, G.M., Gopalakrishnan, S.M., Harris, C.M., Honore, M.P., Kage, K.L., Kapecki, N.J., Ling, C., Ma, J., Mack, H., Mamo, M., Maurus, S., McRae, B., Moore, N.S., Mueller, B.K., Mueller, R., Namovic, M.T., Patel, K., Pratt, S.D., Putman, C.B., Queeney, K.L., Sarris, K.K., Schaffter, L.M., Stoll, V.S., Vasudevan, A., Wang, L., Wang, L., Wirthl, W., Yach, K.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2018-08-01
Resolution2.800
CATH Insert Date16 Dec, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6e9lA01 28 Feb, 2019 1.10.510.10 Assigned
6e9lA02 28 Feb, 2019 3.30.200.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00517 KAPCA_BOVIN Bos taurus cAMP-dependent protein kinase catalytic subunit alpha