PDB Information

PDB6DHA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPAR gamma Drug Pioglitazone.
Mosure, S.A., Shang, J., Eberhardt, J., Brust, R., Zheng, J., Griffin, P.R., Forli, S., Kojetin, D.J.
J. Med. Chem.
HeaderTranscription/Transcription Inhibitor
Released2018-05-18
Resolution1.880
CATH Insert Date17 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6dhaA00 18 Mar, 2019 1.10.565.10 Assigned
6dhaB00 18 Mar, 2019 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P37231 PPARG_HUMAN Homo sapiens Peroxisome proliferator-activated receptor gamma
P37231 PPARG_HUMAN Homo sapiens Peroxisome proliferator-activated receptor gamma