PDB Information

PDB6D1Y
MethodX-RAY DIFFRACTION
Host OrganismInsect cell expression vector pTIE1
Gene SourceHomo sapiens
Primary Citation
Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors.
Bagal, S.K., Omoto, K., Blakemore, D.C., Bungay, P.J., Bilsland, J.G., Clarke, P.J., Corbett, M.S., Cronin, C.N., Cui, J.J., Dias, R., Flanagan, N.J., Greasley, S.E., Grimley, R., Johnson, E., Fengas, D., Kitching, L., Kraus, M.L., McAlpine, I., Nagata, A., Waldron, G.J., Warmus, J.S.
J. Med. Chem.
HeaderTransferase/Inhibitor
Released2018-04-12
Resolution1.930
CATH Insert Date03 Jun, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6d1yA01 29 Jun, 2018 3.30.200.20 Assigned
6d1yA02 29 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P04629 NTRK1_HUMAN Homo sapiens High affinity nerve growth factor receptor