PDB 6cmj

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Overview

PDB Information

PDB	6CMJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model. Price, D.J., Drewry, D.H., Schaller, L.T., Thompson, B.D., Reid, P.R., Maloney, P.R., Liang, X., Banker, P., Buckholz, R.G., Selley, P.K., McDonald, O.B., Smith, J.L., Shearer, T.W., Cox, R.F., Williams, S.P., Reid, R.A., Tacconi, S., Faggioni, F., Piubelli, C., Sartori, I., Tessari, M., Wang, T.Y. Bioorg. Med. Chem. Lett.
Header	Transferase/Transferase Inhibitor
Released	2018-03-05
Resolution	2.400
CATH Insert Date	03 Jun, 2018

PDB Images (3)

Image of CATH 6cmj

6cmj

PDB 6cmj

Image of CATH 6cmjA

6cmjA

PDB Chain 6cmjA

Image of CATH 6cmjB

6cmjB

PDB Chain 6cmjB

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Holding pen
B	03 Jun, 2018	Write scan list

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q96RR4	KKCC2_HUMAN	Homo sapiens	Calcium/calmodulin-dependent protein kinase kinase 2
Q96RR4	KKCC2_HUMAN	Homo sapiens	Calcium/calmodulin-dependent protein kinase kinase 2