Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.
Reich, S.H., Sprengeler, P.A., Chiang, G.G., Appleman, J.R., Chen, J., Clarine, J., Eam, B., Ernst, J.T., Han, Q., Goel, V.K., Han, E.Z.R., Huang, V., Hung, I.N.J., Jemison, A., Jessen, K.A., Molter, J., Murphy, D., Neal, M., Parker, G.S., Shaghafi, M., Sperry, S., Staunton, J., Stumpf, C.R., Thompson, P.A., Tran, C., Webber, S.E., Wegerski, C.J., Zheng, H., Webster, K.R.
J. Med. Chem.