PDB Information

PDB6CCE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Primary Citation
Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Peek, J., Lilic, M., Montiel, D., Milshteyn, A., Woodworth, I., Biggins, J.B., Ternei, M.A., Calle, P.Y., Danziger, M., Warrier, T., Saito, K., Braffman, N., Fay, A., Glickman, M.S., Darst, S.A., Campbell, E.A., Brady, S.F.
Nat Commun
HeaderTranscription/Dna/Antibiotic
Released2018-02-07
Resolution3.050
CATH Insert Date19 Aug, 2018

PDB Images (15)

PDB Prints

PDB Chains (9)

Chain ID Date inserted into CATH CATH Status
A 19 Aug, 2018 Chopped
B 19 Aug, 2018 Chopped
C 19 Aug, 2018 Holding pen
D 19 Aug, 2018 Holding pen
E 19 Aug, 2018 Chopped
F 19 Aug, 2018 Holding pen
G 19 Aug, 2018 Rejected
J 19 Aug, 2018 Rejected
O 19 Aug, 2018 Rejected

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
6cceA01 20 Aug, 2018 3.30.1360.10 Assigned
6cceA02 20 Aug, 2018 2.170.120.12 Assigned
6cceB01 20 Aug, 2018 3.30.1360.10 Assigned
6cceB02 20 Aug, 2018 2.170.120.12 Assigned
6cceE00 20 Aug, 2018 Holding pen

UniProtKB Entries (7)

Accession Gene ID Taxon Description
A0QW02 A0QW02_MYCS2 Mycolicibacterium smegmatis MC2 155 RNA polymerase sigma factor SigA
P60281 RPOB_MYCS2 Mycolicibacterium smegmatis MC2 155 DNA-directed RNA polymerase subunit beta
A0QSL8 RPOA_MYCS2 Mycolicibacterium smegmatis MC2 155 DNA-directed RNA polymerase subunit alpha
A0QWT1 RPOZ_MYCS2 Mycolicibacterium smegmatis MC2 155 DNA-directed RNA polymerase subunit omega
A0QSL8 RPOA_MYCS2 Mycolicibacterium smegmatis MC2 155 DNA-directed RNA polymerase subunit alpha
A0QZ11 RBPA_MYCS2 Mycolicibacterium smegmatis MC2 155 RNA polymerase-binding protein RbpA
A0QS66 RPOC_MYCS2 Mycolicibacterium smegmatis MC2 155 DNA-directed RNA polymerase subunit beta'