PDB Information

PDB6BYH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Gorelik, M., Manczyk, N., Pavlenco, A., Kurinov, I., Sidhu, S.S., Sicheri, F.
Structure
HeaderProtein Binding
Released2017-12-20
Resolution2.610
CATH Insert Date22 Jul, 2018

PDB Images (15)

PDB Prints

PDB Chains (9)

Chain ID Date inserted into CATH CATH Status
A 22 Jul, 2018 Holding pen
B 22 Jul, 2018 Holding pen
C 22 Jul, 2018 Chopped
D 22 Jul, 2018 Chopped
E 22 Jul, 2018 Chopped
F 22 Jul, 2018 Chopped
G 22 Jul, 2018 Holding pen
H 22 Jul, 2018 Chopped
I 22 Jul, 2018 Rejected

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
6byhC00 23 Jul, 2018 Holding pen
6byhD00 23 Jul, 2018 Holding pen
6byhE00 23 Jul, 2018 Holding pen
6byhF00 23 Jul, 2018 Holding pen
6byhH00 23 Jul, 2018 Holding pen

UniProtKB Entries (9)

Accession Gene ID Taxon Description
Q9Y2K7 KDM2A_HUMAN Homo sapiens Lysine-specific demethylase 2A
Q9Y2K7 KDM2A_HUMAN Homo sapiens Lysine-specific demethylase 2A
P0CG47 UBB_HUMAN Homo sapiens Polyubiquitin-B
P63208 SKP1_HUMAN Homo sapiens S-phase kinase-associated protein 1
P63208 SKP1_HUMAN Homo sapiens S-phase kinase-associated protein 1
P0CG47 UBB_HUMAN Homo sapiens Polyubiquitin-B
P0CG47 UBB_HUMAN Homo sapiens Polyubiquitin-B
Q9Y2K7 KDM2A_HUMAN Homo sapiens Lysine-specific demethylase 2A
P63208 SKP1_HUMAN Homo sapiens S-phase kinase-associated protein 1